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Adobe LiveCycle PDFG ES
2021-09-27T22:30:27+05:30
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2021-09-27T22:30:27+05:30
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Journal
International Journal of Hyperthermia
© 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.
38
1
1425-1442
1425
1442
10.1080/02656736.2021.1979254
https://doi.org/10.1080/02656736.2021.1979254
application/pdf
10.1080/02656736.2021.1979254
en-US
ESHO benchmarks for computational modeling and optimization in hyperthermia therapy
Taylor & Francis
International Journal of Hyperthermia, 2021. doi: 10.1080/02656736.2021.1979254
Paulides Margarethus M.
Rodrigues Dario B.
Bellizzi Gennaro G.
Sumser Kemal
Curto Sergio
Neufeld Esra
Montanaro Hazael
Kok H. Petra
Dobsicek Trefna Hana
Hyperthermia
radiofrequency
microwave
treatment planning
computational modeling
VoR
10.1080/02656736.2021.1979254
2021-09-28
True
www.tandfonline.com
10.1080/02656736.2021.1979254
2021-09-28
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/Title(ESHO benchmarks for computational modeling and optimization in hyperthermia therapy)
/ModDate(D:20240328125201+00'00')
/Author(Paulides, M., Rodrigues, D., Bellizzi, G. et al)
/Keywords(microwave, Hyperthermia, radiofrequency, treatment planning, computational modeling, )
/Subject(Background: The success of cancer hyperthermia \(HT\) treatments is strongly dependent on the temperatures achieved in the tumor and healthy tissues as it correlates with treatment efficacy and safety, respectively. Hyperthermia treatment planning \(HTP\) simulations have become pivotal for treatment optimization due to the possibility for pretreatment planning, optimization and decision making, as well as real-time treatment guidance. Materials and methods: The same computational methods deployed in HTP are also used for in silico studies. These are of great relevance for the development of new HT devices and treatment approaches. To aid this work, 3 D patient models have been recently developed and made available for the HT community. Unfortunately, there is no consensus regarding tissue properties, simulation settings, and benchmark applicators, which significantly influence the clinical relevance of computational outcomes. Results and discussion: Herein, we propose a comprehensive set of applicator benchmarks, efficacy and safety optimization algorithms, simulation settings and clinical parameters, to establish benchmarks for method comparison and code verification, to provide guidance, and in view of the 2021 ESHO Grand Challenge \(Details on the ESHO grand challenge on HTP will be provided at https://www.esho.info/\). Conclusion: We aim to establish guidelines to promote standardization within the hyperthermia community such that novel approaches can quickly prove their benefit as quickly as possible in clinically relevant simulation scenarios. This paper is primarily focused on radiofrequency and microwave hyperthermia but, since 3 D simulation studies on heating with ultrasound are now a reality, guidance as well as a benchmark for ultrasound-based hyperthermia are also included.)
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