Single-cell electroporation using a multifunctional pipette
Artikel i vetenskaplig tidskrift, 2012

We present here a novel platform combination, using a multifunctional pipette to individually electroporate single-cells and to locally deliver an analyte, while in their culture environment. We demonstrate a method to fabricate low-resistance metallic electrodes into a PDMS pipette, followed by characterization of its effectiveness, benefits and limits in comparison with an external carbon microelectrode.

cultures

systems

delivery

microfluidic probe

Författare

Alar Ainla

Chalmers, Kemi- och bioteknik, Fysikalisk kemi

Xu Shijun

Chalmers, Kemi- och bioteknik, Fysikalisk kemi

N. Sanchez

Sanofi S.A.

Gavin Jeffries

Chalmers, Kemi- och bioteknik, Fysikalisk kemi

Aldo Jesorka

Chalmers, Kemi- och bioteknik, Fysikalisk kemi

Lab on a Chip - Miniaturisation for Chemistry and Biology

1473-0197 (ISSN) 1473-0189 (eISSN)

Vol. 12 4605-4609

Ämneskategorier

Biokemi och molekylärbiologi

DOI

10.1039/c2lc40563f