Frida Abel

2020

MYO5B mutations in pheochromocytoma/paraganglioma promote cancer progression

Malignant pheochromocytomas/paragangliomas harbor mutations in transport and cell adhesion genes.

Stage-dependent expression of PI3K/Akt‑pathway genes in neuroblastoma.

2013

ERBB3 is a marker of a ganglioneuroblastoma/ganglioneuroma-like expression profile in neuroblastic tumours.

Expression of TWEAK/Fn14 in neuroblastoma: Implications in tumorigenesis

Prevalence of Germline Mutations in Patients with Pheochromocytoma or Abdominal Paraganglioma and Sporadic Presentation: A Population-Based Study in Western Sweden.

2011

A 6-gene signature identifies four molecular subgroups of neuroblastoma

Verification of genes differentially expressed in neuroblastoma tumours: a study of potential tumour suppressor genes.

The Phox2 pathway is differentially expressed in neuroblastoma tumors, but no mutations were found in the candidate tumor suppressor gene PHOX2A.

High incidence of DNA mutations and gene amplifications of the ALK gene in advanced sporadic neuroblastoma tumours.

High incidence of DNA mutations and gene amplifications of the ALK gene in advanced sporadic neuroblastoma tumours

Gene expression variation to predict 10-year survival in lymph-node-negative breast cancer.

No germline mutations in supposed tumour suppressor genes SAFB1 and SAFB2 in familial breast cancer with linkage to 19p

Significant Decrease in mRNA Expression of Five Genes Mapped at 1p36.2, comparing Favorable and Unfavorable Neuroblastomas.

Imbalance of the mitochondrial pro- and anti-apoptotic mediators in neuroblastoma tumours with unfavourable biology.

A novel 1p36.2 located gene, APITD1, with tumour-suppressive properties and a putative p53-binding domain, shows low expression in neuroblastoma tumours.

Genetic studies of neuroblastoma with emphasis on the apoptotic pathway

Investigation of the role of SDHB inactivation in sporadic phaeochromocytoma and neuroblastoma.

Mutations in the N-terminal domain of DFF45 in a primary germ cell tumor and in neuroblastoma tumors.

Screening for gene mutations in a 500 kb neuroblastoma tumor suppressor candidate region in chromosome 1p; mutation and stage-specific expression in UBE4B/UFD2.

Analyses of apoptotic regulators CASP9 and DFFA at 1P36.2, reveal rare allele variants in human neuroblastoma tumours.

Fine mapping of a tumour suppressor candidate gene region in 1p36.2-3, commonly deleted in neuroblastomas and germ cell tumours.

Fine mapping of the human preprocortistatin gene (CORT) to neuroblastoma consensus deletion region 1p36.3-->p36.2, but absence of mutations in primary tumors.

Gain of chromosome arm 17q is associated with unfavourable prognosis in neuroblastoma, but does not involve mutations in the somatostatin receptor 2(SSTR2) gene at 17q24.