Hybrid MEG-MRI Imaging System (MEGMRI)

We will develop and validate hybrid magnetoencephalography (MEG) and magnetic resonance imaging (MRI) technology that will allow simultaneous structural (MRI) and functional (MEG) imaging of the human brain. MEG is a non-invasive 3D functional imaging with a high temporal resolution compared to other functional imaging but often suffers from a precise structural localization which will be solved by the dual modality approach of the MEGMRI hybrid scanner. In parallel, low field MRI, a new very promising alternative to conventional high field MRI will provide enhanced image contrast in certain applications, improved geometric accuracy, improve safety (for patient with pacemakers and other implants, for pregnant women, for infants), and reduce costs. These new opportunities are based on recent advances in ultra-sensitive magnetic sensors. Superconducting magnetometers based on quantum interference devices (SQUIDs) have been recently used to provide 2D-MRI images at very low fields by two US teams. In parallel, a new type of magnetometer, called mixed sensor, based on spin electronics devices, has been developed within our consortium and used for low-field NMR. The first part of the project will be focused on sensor optimization, and low-field MRI development. This covers the development of field-tolerant SQUIDs and optimized mixed sensors and 3D-MRI low-field hardware and software development. The second part of the project will be devoted to a prototype building with the best kind of sensor and extensive preclinical validation, covering major brain disorders for adults and children. The consortium of MEGMRI has the necessary skills to perform all the tasks: sensor developers, MRI experts, MEG developers and clinical validators. It contains 13 partners from 5 countries including 3 SMEs and one large medical device manufacturer.

Participants

Dag Winkler (contact)

Professor vid Chalmers, Microtechnology and Nanoscience (MC2)

Collaborations

Aalto University, Espoo

Espoo, Finland

Aivon Oy

Helsinki, Finland

Associazone Fatebenefratelli per la Ricerca

Rome, Italy

Cedrat Technologies

Meylan, France

Elekta

Stockholm, Sweden

G. d'Annunzio University of Chieti-Pescara

Chieti, Italy

Hospital District of Helsinki and Uusimaa (HUS)

Helsinki, Finland

Imaging Technology Abruzzo S.r.l.

L'Aquila, Italy

Physikalisch-Technische Bundesanstalt (PTB)

Braunschweig, Germany

Technical Research Centre of Finland (VTT)

Espoo, Finland

The French Alternative Energies and Atomic Energy Commission (CEA)

Grenoble Cedex 09, France

University of Parma

Parma, Italy

Funding

European Commission (FP7)

Funding years 2013

European Commission (FP7)

Funding years 2008–2012

Related Areas of Advance and Infrastructure

Sustainable development

Driving Forces

More information

Project Web Page

http://www.megmri.net/

Latest update

2015-12-10