Assessment of fracture risk
Journal article, 2009
Fractures are a common complication of osteoporosis. Although osteoporosis is defined by bone mineral density at the femoral neck, other sites and validated techniques can be used for fracture prediction. Several clinical risk factors contribute to fracture risk independently of BMD. These include age, prior fragility fracture, smoking, excess alcohol, family history of hip fracture, rheumatoid arthritis and the use of oral glucocorticoids. These risk factors in conjunction with BMD can be integrated to provide estimates of fracture probability using the FRAX tool. Fracture probability rather than BMD alone can be used to fashion strategies for the assessment and treatment of osteoporosis.
methods
Incidence
Humans
diagnosis
Fractures
Bone Density
Osteoporosis
Age Distribution
Proportional Hazards Models
Risk Assessment
epidemiology
diagnosis
Decision Support Systems
Risk Factors
epidemiology
Clinical
Bone
Author
John A Kanis
Helena Johansson
University of Gothenburg
Anders Odén
Eugene V McCloskey
European Journal of Radiology
0720-048X (ISSN) 18727727 (eISSN)
Vol. 71 3 392-7Subject Categories
Endocrinology and Diabetes
Physiology
DOI
10.1016/j.ejrad.2008.04.061
PubMed
19716672