Model drug release from matrix tablets composed of HPMC with different substituent heterogeneity
Journal article, 2010
gelation
Hydrophilic matrix tablets
polymer
erosion
Chemical heterogeneous
behavior
hydrophilic
Batch-to-batch variation
methylcellulose
matrices
Hydroxypropyl
enzymatic degradation
hydroxypropyl methylcellulose
trichoderma-reesei
methyl cellulose
solubility
Drug release
Author
Anna Viridén
SuMo Biomaterials
Chalmers, Chemical and Biological Engineering, Pharmaceutical Technology
Anette Larsson
Chalmers, Chemical and Biological Engineering, Pharmaceutical Technology
SuMo Biomaterials
H. Schagerlof
Lund University
Bengt Wittgren
AstraZeneca AB
International Journal of Pharmaceutics
0378-5173 (ISSN) 1873-3476 (eISSN)
Vol. 401 1-2 60-67Subject Categories
Pharmaceutical Sciences
DOI
10.1016/j.ijpharm.2010.09.017