2D Bipyrimidine silver(I) nitrate: Synthesis, X-ray structure, solution chemistry and anti-microbial activit
Journal article, 2011

Synthesis and X-ray single crystal structure analysis of the compound {[Ag2(μ2-bpym)(μ-O-NO3)2]}n, (1), (where bpym = 2,2′-bipyrimidine) are presented. Compound (1) has a (6,3)-2D honeycomb structure with a tetrahedral coordination geometry around the Ag(I) ion. In contrary to the solid state structural investigation, ESI-MS for (1) in solution shows a strong peak at m/z 423.0269 which indicates that the [Ag(bpym)2]+ cation is dominating instead of [Ag2(bpym)]2+. The anti-microbial activity of (1) was screened against 15 multi-drug resistant bacteria in comparison to silver(I) sulphadiazine and it showed a high activity against Burkholderia mallei which causes glanders; with a MIC value of 4 μg/ml.

X-ray structure


Anti-microbial activity

Silver(I) compounds

2 '-bipyrimidine


Al-Shimaà A A Massoud

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Vratislav Langer

Chalmers, Chemical and Biological Engineering, Environmental Inorganic Chemistry

Yousry M. Gohar

Morsy A.M. Abu-Youssef

Janne Jänis

Lars Öhrström

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Inorganic Chemistry Communication

1387-7003 (ISSN)

Vol. 14 4 550-553

Subject Categories

Inorganic Chemistry

Chemical Sciences

Areas of Advance

Life Science Engineering (2010-2018)



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