Do we need fractionation-corrected doses in sequential two-phase treatments? A quantification of dose differences between non-corrected and corrected combined non-uniform dose distributions in normal tissue.
Journal article, 2010
For many tumour sites, external beam radiation therapy (EBRT) is delivered with a sequential two-phase treatment regime. Yet, there is a lack of consensus of how to add two different non-uniform dose distributions in order to evaluate the late radiation effect for normal tissue. The purpose of this novel investigation is to quantify the dose differences between non-corrected and fractionation-corrected combined non-uniform dose distributions.
Dose Fractionation
Relative Biological Effectiveness
Mathematical Computing
methods
Radiotherapy Planning
Linear Models
Humans
Radiotherapy
Computer-Assisted
Author
Caroline Olsson
University of Gothenburg
Karl-Axel Johansson
University of Gothenburg
Acta Oncologica
0284-186X (ISSN) 1651-226X (eISSN)
Vol. 49 8 1253-1260Subject Categories (SSIF 2011)
Radiology, Nuclear Medicine and Medical Imaging
Cancer and Oncology
DOI
10.3109/0284186X.2010.492788
PubMed
20586660