Investigating the yet-unknown biomass degrading and modifying enzymes of Aspergillus oryzae

Conference poster, 2011

The associations of plant cell wall components with A. oryzae’s extracellular enzyme machinery were investigated from a chemical perspective using an integrated analysis of the transcriptome profile. We were able to identify novel hydrolases, which we heterologous expressed for subsequent characterization. This work represents a novel way of integrating computational chemical biology and classical enzyme research for improving lignocellulose bioconversion. In this work, we aim at the heterologous expression and characterization of seven different hypothetical and non classified proteins of A. oryzae, which could prove to be useful tools in the wood biomass separation and modification process.