Single-cell electroporation using a multifunctional pipette
Journal article, 2012

We present here a novel platform combination, using a multifunctional pipette to individually electroporate single-cells and to locally deliver an analyte, while in their culture environment. We demonstrate a method to fabricate low-resistance metallic electrodes into a PDMS pipette, followed by characterization of its effectiveness, benefits and limits in comparison with an external carbon microelectrode.

cultures

systems

delivery

microfluidic probe

Author

Alar Ainla

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Xu Shijun

Chalmers, Chemical and Biological Engineering, Physical Chemistry

N. Sanchez

Sanofi S.A.

Gavin Jeffries

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Aldo Jesorka

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Lab on a Chip - Miniaturisation for Chemistry and Biology

1473-0197 (ISSN) 1473-0189 (eISSN)

Vol. 12 22 4605-4609

Subject Categories

Biochemistry and Molecular Biology

DOI

10.1039/c2lc40563f

More information

Created

10/7/2017