Serum concentrations of VEGF and b-FGF in renal cell, prostate and urinary bladder carcinomas.
Journal article, 1999
Sixty nine patients with urogenital cancers (renal, bladder and prostate cancer) were studied to determine whether the serum concentrations of Vascular Endothelial Growth Factor (VEGF) and basic Fibroblast Growth Factor (b-FGF) reflected the status of the patients and/or the prognosis of the disease. Of the patients included in this study, renal cell carcinoma patients expressed the highest levels of VEGF indicating that these tumours are more VEGF dependent. The values of b-FGF could be considered normal in all three malignancies. No correlation was observed between the expression of VEGF and b-FGF, nor between VEGF and b-FGF and patients survival.
Middle Aged
80 and over
blood
Fibroblast Growth Factor 2
Kidney Neoplasms
Aged
blood
Endothelial Growth Factors
Adult
blood
Prostatic Neoplasms
Female
Vascular Endothelial Growth Factors
Vascular Endothelial Growth Factor A
Carcinoma
Lymphokines
Male
blood
Humans
Renal Cell
Urinary Bladder Neoplasms
Enzyme-Linked Immunosorbent Assay
Aged
blood
blood
blood
Author
M Edgren
Bo Lennernäs
A Larsson
Staffan Nilsson
Anticancer Research
0250-7005 (ISSN) 17917530 (eISSN)
Vol. 19 1B 869-73Subject Categories
Cancer and Oncology
PubMed
10216508