Evidence for hydrophobic catalysis of DNA strand exchange
Journal article, 2015

The catalytic role of hydrophobic co-solutes in DNA strand exchange is demonstrated by FRET kinetics. Two mechanisms that contribute to this are base stacking destabilisation and nucleation-promoted DNA strand invasion. We propose that hydrophobic catalysis is involved in the strand-exchange activity of recombination enzymes.

Author

Bobo Feng

Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry, Physical Chemistry

Fredrik Westerlund

Chalmers, Biology and Biological Engineering, Chemical Biology

Bengt Nordén

Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry, Physical Chemistry

Chemical Communications

1359-7345 (ISSN)

Vol. 51 34 7390-7392

Areas of Advance

Nanoscience and Nanotechnology (2010-2017)

Life Science Engineering (2010-2018)

Subject Categories

Physical Chemistry

DOI

10.1039/c5cc01515d

More information

Created

10/7/2017