Benchmarking for On-Scalp MEG Sensors
Journal article, 2017

Objective: We present a benchmarking protocol for quantitatively comparing emerging on-scalp magnetoencephalography (MEG) sensor technologies to their counterparts in state-of-the-art MEG systems. Methods: As a means of validation, we compare a high-critical-temperature superconducting quantum interference device (high T-c SQUID) with the low-T-c SQUIDs of an Elekta Neuromag TRIUX system in MEG recordings of auditory and somatosensory evoked fields (SEFs) on one human subject. Results: We measure the expected signal gain for the auditory-evoked fields (deeper sources) and notice some unfamiliar features in the on-scalp sensor-based recordings of SEFs (shallower sources). Conclusion: The experimental results serve as a proof of principle for the benchmarking protocol. This approach is straightforward, general to various on-scalp MEG sensors, and convenient to use on human subjects. The unexpected features in the SEFs suggest on-scalp MEG sensors may reveal information about neuromagnetic sources that is otherwise difficult to extract from state-of-the-art MEG recordings. Significance: As the first systematically established on-scalp MEG benchmarking protocol, magnetic sensor developers can employ this method to prove the utility of their technology in MEG recordings. Further exploration of the SEFs with on-scalp MEG sensors may reveal unique information about their sources.

high-temperature

dipole

system

Auditory and somatosensory evoked fields (AEF and SEF)

Engineering

brain

benchmark

Author

Minshu Xie

University of Technology

Justin Schneiderman

Sahlgrenska Academy

Maxim Chukharkin Leonidovich

Chalmers, Microtechnology and Nanoscience (MC2), Quantum Device Physics

Alexei Kalaboukhov

Chalmers, Microtechnology and Nanoscience (MC2), Quantum Device Physics

B. Riaz

Sahlgrenska Academy

D. Lundqvist

Karolinska Institutet

S. Whitmarsh

Karolinska Institutet

M. Hämäläinen

Aalto University

Karolinska Institutet

V. Jousmäki

Karolinska Institutet

Aalto University

R. Oostenveld

Karolinska Institutet

Radboud University

Dag Winkler

Chalmers, Microtechnology and Nanoscience (MC2), Quantum Device Physics

IEEE Transactions on Biomedical Engineering

0018-9294 (ISSN)

Vol. 64 6 1270-1276

Subject Categories

Biomedical Laboratory Science/Technology

DOI

10.1109/tbme.2016.2599177

More information

Latest update

3/23/2018