Bacterial biofilm elimination using gold nanorod localised surface plasmon resonance generated heat
Journal article, 2017

Antimicrobial resistance is an increasing global health concern and the world is facing a major challenge to develop novel ways of replacing antibiotics. Gold nanorods exhibit localised surface plasmon resonance upon optical irradiation. During relaxation, absorbed energy is dissipated as heat, which has been utilized to kill bacteria. In this study, 10 x 45 nm gold nanorods were attached to glass surfaces using silanisation. Then biofilms were cultured on the surfaces and studied using microscopy. On average, 71% of the early biofilm bacteria were eliminated after 5 min of near infrared radiation (LED emission peak at 850 nm) of the gold nanorod coated surfaces, showing the potential of this novel antibiofilm technique. Most notably, the best individual result showed 97% biofilm elimination. This study demonstrates that nanoplasmonic generated heat offers a novel way of eliminating bacterial biofilms. In future applications, this method may be used to eliminate bacterial contamination during implant surgery.

Localisea surface plasmon resonance

Gold nanorods

Photothermal therapy

Staphylococcus epiderrnidis

Biofilm

Author

Maria Pihl

Chalmers, Chemistry and Chemical Engineering, Applied Chemistry

E.M. Bruzell

Nordisk Institutt for Odontologiske Materialer

Martin Andersson

Chalmers, Chemistry and Chemical Engineering, Applied Chemistry

Materials Science and Engineering C

0928-4931 (ISSN) 18730191 (eISSN)

Vol. 80 54-58

Subject Categories

Materials Chemistry

DOI

10.1016/j.msec.2017.05.067

More information

Created

10/8/2017