Femtosecond X-ray Fourier holography imaging of free-flying nanoparticles
Journal article, 2018
Ultrafast X-ray imaging on individual fragile specimens such as aerosols 1 , metastable particles 2 , superfluid quantum systems 3 and live biospecimens 4 provides high-resolution information that is inaccessible with conventional imaging techniques. Coherent X-ray diffractive imaging, however, suffers from intrinsic loss of phase, and therefore structure recovery is often complicated and not always uniquely defined 4,5 . Here, we introduce the method of in-flight holography, where we use nanoclusters as reference X-ray scatterers to encode relative phase information into diffraction patterns of a virus. The resulting hologram contains an unambiguous three-dimensional map of a virus and two nanoclusters with the highest lateral resolution so far achieved via single shot X-ray holography. Our approach unlocks the benefits of holography for ultrafast X-ray imaging of nanoscale, non-periodic systems and paves the way to direct observation of complex electron dynamics down to the attosecond timescale.
Author
Tais Gorkhover
Stanford University
Technische Universität Berlin
Anatoli Ulmer
Technische Universität Berlin
Ken Ferguson
Stanford University
Max Bucher
Technische Universität Berlin
Stanford University
Argonne National Laboratory
Filipe R.N.C. Maia
Lawrence Berkeley National Laboratory
Uppsala University
Johan Bielecki
European XFEL
Uppsala University
Tomas Ekeberg
Deutsches Elektronen-Synchrotron (DESY)
Max F. Hantke
Uppsala University
Benedikt J. Daurer
Uppsala University
Carl Nettelblad
Uppsala University
Jakob Andreasson
Uppsala University
Chalmers, Physics, Condensed Matter Physics
Czech Academy of Sciences
Anton Barty
Deutsches Elektronen-Synchrotron (DESY)
Petr Bruza
Czech Academy of Sciences
Sebastian Carron
Stanford University
Dirk Hasse
Uppsala University
Jacek Krzywinski
Stanford University
Daniel S.D. Larsson
Uppsala University
Andrew Morgan
Deutsches Elektronen-Synchrotron (DESY)
Kerstin Mühlig
Uppsala University
Maria Müller
Technische Universität Berlin
Kenta Okamoto
Uppsala University
Alberto Pietrini
Uppsala University
Daniela Rupp
Technische Universität Berlin
Mario Sauppe
Technische Universität Berlin
Gijs Van Der Schot
Uppsala University
Marvin Seibert
Uppsala University
Jonas A. Sellberg
Uppsala University
AlbaNova University Center
Martin Svenda
Uppsala University
Michelle Swiggers
Stanford University
N. Timneanu
Uppsala University
Daniel Westphal
Uppsala University
Garth Williams
Stanford University
Brookhaven National Laboratory
Alessandro Zani
Uppsala University
H. N. Chapman
Deutsches Elektronen-Synchrotron (DESY)
Gyula Faigel
Hungarian Academy of Sciences
Thomas Möller
Technische Universität Berlin
Janos Hajdu
Czech Academy of Sciences
Uppsala University
European XFEL
Christoph Bostedt
Argonne National Laboratory
Northwestern University
Stanford University
Nature Photonics
1749-4885 (ISSN) 17494893 (eISSN)
Vol. 12 3 150-153Subject Categories
Astronomy, Astrophysics and Cosmology
Atom and Molecular Physics and Optics
Other Physics Topics
DOI
10.1038/s41566-018-0110-y