Hyperbaric Oxygen Acutely Increases Wound Circulation as Assessed by Fluorescent Angiography
Paper in proceedings, 2016

The efficacy of hyperbaric oxygen therapy (HBOT) to facilitate wound healing in diabetic lower extremity ulcers is well established. The exact mechanism of HBOT-mediated wound healing is unclear but is thought to relate to increased reactive oxygen species and reactive nitrogen species (ROS and RNS). ROS and RNS lead to many downstream affects that impact wound healing, including increased growth factors, diminished inflammatory responses, and improved neovascularization. The impact of HBOT, however, on tissue perfusion and flow is not known. The purpose of this pilot study was to ascertain the immediate effects of HBOT on the microvasculature of chronic wounds as assessed by fluorescent angiography.

Angiography

Hyperbaric oxygene treatment

Diabetic foot ulcer

Author

Sarah C. Sorice

Unknown organization

Torbjörn Lundh

Chalmers, Mathematical Sciences, Applied Mathematics and Statistics

Geoffrey C. Gurtner

Unknown organization

Shannon Meyer

Stanford University

Subhro Sen

Stanford University

Robert Robertson

Stanford University

Jeanie Parsley

Stanford University

Journal of Vascular Surgery

0741-5214 (ISSN) 1097-6809 (eISSN)

Vol. 63 6 100S-101S

Vascular Annual Meeting
Washington, DC, USA,

Subject Categories

Surgery

Cardiac and Cardiovascular Systems

Radiology, Nuclear Medicine and Medical Imaging

Areas of Advance

Life Science Engineering

DOI

10.1016/j.jvs.2016.03.112

More information

Latest update

4/3/2018 2