Inosine triphosphate pyrophosphatase dephosphorylates ribavirin triphosphate and reduced enzymatic activity potentiates mutagenesis in hepatitis C virus
Journal article, 2018
ITPA
Ribavirin
Mutagenesis
ITPase
Inosine triphosphate pyrophosphatase
Mutagenesis
ITP pyrophosphatase
hepatitis C virus
Author
Kristina Nyström
University of Gothenburg
Paulina Wanrooij
Umeå University
Jesper Waldenström
University of Gothenburg
Ludmila Adamek
University of Gothenburg
Sofia Brunet
University of Gothenburg
Joanna Said
University of Gothenburg
Staffan Nilsson
University of Gothenburg
Chalmers, Mathematical Sciences, Applied Mathematics and Statistics
Megan Wind-Rotolo
Bristol-Myers Squibb
Kristoffer Hellstrand
University of Gothenburg
Helene Norder
University of Gothenburg
Ka Wei Tang
University of Gothenburg
Wallenberg Lab.
Martin Lagging
University of Gothenburg
Journal of Virology
0022-538X (ISSN) 1098-5514 (eISSN)
Vol. 92 19 e01087Subject Categories
Microbiology
Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
Microbiology in the medical area
DOI
10.1128/JVI.01087-18
PubMed
30045981