Unraveling the potential of non-conventional yeasts in biotechnology
Journal article, 2022

Cost-effective microbial conversion processes of renewable feedstock into biofuels and biochemicals are of utmost importance for the establishment of a robust bioeconomy. Conventional baker's yeast Saccharomyces cerevisiae, widely employed in biotechnology for decades, lacks many of the desired traits for such bioprocesses like utilization of complex carbon sources or low tolerance towards challenging conditions. Many non-conventional yeasts (NCY) present these capabilities, and they are therefore forecasted to play key roles in future biotechnological production processes. For successful implementation of NCY in biotechnology, several challenges including generation of alternative carbon sources, development of tailored NCY and optimization of the fermentation conditions are crucial for maximizing bioproduct yields and titers. Addressing these challenges requires a multidisciplinary approach that is facilitated through the 'YEAST4BIO' COST action. YEAST4BIO fosters integrative investigations aimed at filling knowledge gaps and excelling research and innovation, which can improve biotechnological conversion processes from renewable resources to mitigate climate change and boost transition towards a circular bioeconomy. In this perspective, the main challenges and research efforts within YEAST4BIO are discussed, highlighting the importance of collaboration and knowledge exchange for progression in this research field.

volatile fatty acids

lignocellulosic sugars

biofuels

biochemicals

non-conventional yeasts

Author

Cecilia Geijer

Chalmers, Biology and Biological Engineering, Industrial Biotechnology

R. Ledesma-Amaro

Imperial College London

Elia Tomas-Pejo

IMDEA Energy Institute

FEMS Yeast Research

1567-1356 (ISSN) 1567-1364 (eISSN)

Vol. 22 1 foab071

Subject Categories

Social Sciences Interdisciplinary

Other Engineering and Technologies not elsewhere specified

Information Systemes, Social aspects

DOI

10.1093/femsyr/foab071

PubMed

35040953

More information

Latest update

3/14/2022