Systems Biology in ELIXIR: modelling in the spotlight
Journal article, 2022
In this white paper, we describe the founding of a new ELIXIR Community - the Systems Biology Community - and its proposed future contributions to both ELIXIR and the broader community of systems biologists in Europe and worldwide. The Community believes that the infrastructure aspects of systems biology - databases, (modelling) tools and standards development, as well as training and access to cloud infrastructure - are not only appropriate components of the ELIXIR infrastructure, but will prove key components of ELIXIR's future support of advanced biological applications and personalised medicine. By way of a series of meetings, the Community identified seven key areas for its future activities, reflecting both future needs and previous and current activities within ELIXIR Platforms and Communities. These are: overcoming barriers to the wider uptake of systems biology; linking new and existing data to systems biology models; interoperability of systems biology resources; further development and embedding of systems medicine; provisioning of modelling as a service; building and coordinating capacity building and training resources; and supporting industrial embedding of systems biology. A set of objectives for the Community has been identified under four main headline areas: Standardisation and Interoperability, Technology, Capacity Building and Training, and Industrial Embedding. These are grouped into short-term (3-year), mid-term (6-year) and long-term (10-year) objectives.
Network Biology
FAIR
ELIXIR Communities
Biotechnology
Systems Medicine
Biomolecular Models
Biological data
Systems Biology
Author
Vitor Martins Dos Santos
Wageningen University and Research
Petre Mihail Anton
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
Barbara Szomolay
Cardiff University
Marek Ostaszewski
University of Luxembourg
Ilja Arts
Maastricht University
Rui Benfeitas
Science for Life Laboratory (SciLifeLab)
Victoria Dominguez Del Angel
GENOPOLE
Polonca Ferk
University of Ljubljana
Dirk Fey
University College Dublin
Carole Goble
University of Manchester
Martin Golebiewski
Heidelberg Institute for Theoretical Studies (HITS GmbH)
Kristina Gruden
National Institute of Biology Ljubljana
Katharina F. Heil
ELIXIR Hub
Henning Hermjakob
European Bioinformatics Institute
Pascal Kahlem
Scientific Network Management S.L.
Maria I. Klapa
Institute of Chemical Engineering and High Temperature Chemical Processes
Jasper J. Koehorst
Wageningen University and Research
Alexey Kolodkin
Luxembourg Institute of Health
Vrije Universiteit Amsterdam
Martina Kutmon
Maastricht University
Brane Leskošek
University of Ljubljana
Sébastien Moretti
Swiss Institute of Bioinformatics
Wolfgang Müller
Heidelberg Institute for Theoretical Studies (HITS GmbH)
Marco Pagni
Swiss Institute of Bioinformatics
Tadeja Rezen
University of Ljubljana
Miguel Rocha
University of Minho
Damjana Rozman
University of Ljubljana
David Šafránek
Masaryk University
Rahuman S.Malik Sheriff
European Bioinformatics Institute
Maria Suarez Diez
Wageningen University and Research
Kristel Van Steen
KU Leuven
University of Liège
Hans V. Westerhoff
Vrije Universiteit Amsterdam
Ulrike Wittig
Heidelberg Institute for Theoretical Studies (HITS GmbH)
Katherine Wolstencroft
Leiden University
Anze Zupanic
National Institute of Biology Ljubljana
Chris T. Evelo
Maastricht University
John M. Hancock
University of Ljubljana
F1000Research
2046-1402 (ISSN) 1759796x (eISSN)
Vol. 11Subject Categories
Other Computer and Information Science
Embedded Systems
Computer Systems
DOI
10.12688/f1000research.126734.2
PubMed
36742342