MnFe2 O4 Nanoparticles-Catalyzed C3-Alkylation of Indoles with Benzyl Alcohols under Solvent-Free Conditions
Journal article, 2024
Herein, we present an efficient, one-pot reaction for accessing 3-benzylated indoles via the coupling of benzyl alcohols with indoles under heterogeneous catalysis by manganese ferrite (MnFe2O4) nanoparticles. Notably, this reaction, for the first time, employs MnFe2O4 nanoparticles prepared using a simple grinding method. The high compatibility of MnFe2O4 nanoparticles enables a broad substrate scope and high regioselectivity. Moreover, this approach offers several attractive highlights including the use of a recyclable oxide catalyst and green and cost-effective alkylating reagents under solvent-free conditions.
C3-alkylation
Benzyl alcohol
Indole
MnFe O 2 4
Heterogeneous catalysis
Author
Ha V. Le
Vietnam National University
Ho Chi Minh City University of Technology (HCMUT)
Huy X. Le
Vietnam National University
Ho Chi Minh City University of Technology (HCMUT)
Vy T.B. Nguyen
Vietnam National University
Ho Chi Minh City University of Technology (HCMUT)
Tu T. Le
Ho Chi Minh City University of Technology (HCMUT)
Vietnam National University
Hanh N. Nguyen
Vietnam National University
Ho Chi Minh City University of Technology (HCMUT)
Thuong T.H. Nguyen
Ho Chi Minh City University of Technology (HCMUT)
Vietnam National University
Tung T. Nguyen
Vietnam National University
Ho Chi Minh City University of Technology (HCMUT)
Hoang Phuoc Ho
Chalmers, Chemistry and Chemical Engineering, Chemical Technology
Khoa D. Nguyen
Vietnam National University
Ho Chi Minh City University of Technology (HCMUT)
Dat P. Tran
Ho Chi Minh City University of Technology (HCMUT)
Vietnam National University
ChemistrySelect
2365-6549 (eISSN)
Vol. 9 33 e202402007Subject Categories
Materials Chemistry
Organic Chemistry
DOI
10.1002/slct.202402007