Ring-shaped nanoparticle assembly and cross-linking on lipid vesicle scaffolds
Journal article, 2024

We show the assembly of carboxylate-modified polystyrene nanoparticles into flexible circular, ring-shaped structures with micrometer sized diameters around the base of surface-adhered lipid vesicles. The rings remain around the vesicles but disintegrate when the lipid membranes are dissolved in detergent. The aqueous medium allows carbodiimide-based cross-linking chemistry to be applied to the particle assemblies resulting in the preservation of the rings even after the lipid compartments are dissolved.

Carbodiimides

Lipid vesicles

Shaped nanoparticles

Polystyrene nanoparticles

Aqueous media

Circular ring

Ring shaped structures

Lipid membranes

Nanoparticle cross-linking

Nanoparticle assemblies

Author

Gizem Karabiyik

University of Oslo

Aldo Jesorka

Chalmers, Chemistry and Chemical Engineering

Irep Gözen

University of Oslo

Soft Matter

1744-683X (ISSN) 1744-6848 (eISSN)

Vol. 20 45 8947-8951

Chemical Reaction Networks: signal amplification, spatiotemporal control, and materials (CReaNet)

European Commission (EC) (EC/H2020/812868), 2019-04-01 -- 2023-03-01.

Proto-Opto-Electro-Mechanical Hybrid Systems for Generation-Next Bionic Devices (PROGENY)

European Commission (EC) (EC/H2020/899205), 2021-01-01 -- 2024-06-30.

Subject Categories (SSIF 2025)

Cell and Molecular Biology

DOI

10.1039/d4sm01010h

PubMed

39508507

More information

Latest update

5/20/2025