Fluorescence Labelling of RNA and Its Impact on Lipid Nanoparticle Structures
Doctoral thesis, 2026
Awaiting approval from collaborating industry to publish the work.
small-angle scattering
fluorescent base analogues
lipid nanoparticles
fluorescence
RNA
Author
Alma Karlsson
Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry
Increased brightness of fluorescent uridine, qU, inside single- and double-stranded RNA
Scientific Reports,;Vol. 16(2026)
Journal article
Expanding fluorescent base analogue labelling of long RNA by in vitro transcription
Journal of Biological Chemistry,;Vol. 301(2025)
Journal article
Alma F. E. Karlsson, Hoang-Ngoan Le, Tim Pfister, Josefine Järvdalen, Tove Slagbrand, Anders Dahlén, L. Marcus Wilhelmsson. Synthesis and characterisation of a redshifted, pH-responsive tricyclic guanosine analogue
Alma F. E. Karlsson, James Doutch, Josefine Järvdalen, Jennifer Gilbert, Hanna M. G. Barriga, Margaret N. Holme, L. Marcus Wilhelmsson. Effects on RNA fluorescence labelling on internal lipid nanoparticle structures
Awaiting approval from collaborating industry to publish the work.
Funktionell leverans av nukleotid-baserade läkemedel
Swedish Foundation for Strategic Research (SSF) (IRC15-0065), 2017-03-01 -- 2024-12-31.
Endogenous non-invasive fluorescence labeling of RNA and its use in cell imaging
Swedish Research Council (VR) (2021-04409), 2021-12-01 -- 2025-11-30.
Areas of Advance
Nanoscience and Nanotechnology
Subject Categories (SSIF 2025)
Physical Chemistry
DOI
10.63959/chalmers.dt/5971
ISBN
978-91-8103-514-8
Doktorsavhandlingar vid Chalmers tekniska högskola. Ny serie: 5971
Publisher
Chalmers