2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-3,8-dimethyl-4H-1-benzopyran-4-one

Journal article, 2002

The crystal structure of 2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-3,8-dimethyl-4H-1-benzopyran-4-one (alternatively 3',4'-dimethoxyphenyl-5,7-dimethoxy-3,8-dimethylflavone),C21H22O6, known to be a potent and selective inhibitor of rat heart cytosolic cyclic nucleotide phosphodiesterases, has been determined. In the benzopyran ring system, the pyran ring is slightly puckered. The structure is stabilized by weak C-H...O hydrogen bonds and by π-π interactions between pyran rings.