Chemical measurements in Drosophila
Journal article, 2009
The fruit fly, Drosophila melanogaster, has been extensively used as a model organism in genetics research and has significantly contributed to understanding molecular, cellular and evolutionary aspects of human behavior. Recently, research has focused on developing analytical methods to obtain highly sensitive chemical quantification along with spatiotemporal information from Drosophila melanogaster. We review a number of these advances in capillary electrophoresis, high-performance liquid chromatography, mass spectrometry, and technologies involving intact organisms, including in vivo electrochemistry.
Mass spectrometry
High-performance liquid chromatography
Larvae
Micellar electrokinetic chromatography
in vivo electrochemistry
Drosophila
Microfluidics
RNA interference
Galactosidase-4-upstream activating sequences
RNAi
DAT
GAL4-UAS
Capillary electrophoresis
Dopamine transporter
MEMS-based system
Embryo
Author
Monique A. Makos
Nicholas J. Kuklinski
University of Gothenburg
M. L. Heien
Andrew Ewing
University of Gothenburg
E. C. Berglund
University of Gothenburg
TrAC - Trends in Analytical Chemistry
0165-9936 (ISSN)
Vol. 28 11 1223-1234Subject Categories
Chemical Sciences