Resonant neutral particle emission in collisions of electrons with protonated peptides with disulfide bonds at high energies
Journal article, 2011
Electron-ion collisions were studied for various protonated peptide monocations with disulfide bonds, using an electrostatic storage-ring equipped with a merged-electron-beam device. Resonant neutral particle emissions at the energies of 6-7 eV were observed, as well as a rise towards zero-energy, which are typical electron-capture dissociation profiles. The presence of disulfide (S-S) bonds tends to enhance the resonant bump heights. Chemical nature of the amino-acid residues adjacent to cysteines appears to correlate with the bump strength. Molecular-dynamical simulations help clarify the role of molecular vibration modes in the electron-capture dissociation process. (C) 2011 Elsevier B. V. All rights reserved.
gas-phase
ion/ion reactions
polypeptide ions
hydrogen-atom adducts
electrostatic storage-ring
capture
attachment
dissociation
amide bond
peptides
model peptide
helical
Author
T. Tanabe
National Institute of Radiological Sciences
High Energy Accelerator Research Organization
K. Noda
National Institute of Radiological Sciences
S. Miyagi
Toyohashi University of Technology
N. Kurita
Toyohashi University of Technology
S. Tanaka
Kobe University
J. Setzler
Karlsruhe Institute of Technology (KIT)
W. Wenzel
Karlsruhe Institute of Technology (KIT)
Evgeni B. Starikov
Chalmers, Chemical and Biological Engineering, Physical Chemistry
G. Cuniberti
Technische Universität Dresden
Pohang University of Science and Technology
Chemical Physics Letters
0009-2614 (ISSN)
Vol. 504 1-3 83-87Subject Categories
Physical Chemistry
DOI
10.1016/j.cplett.2011.01.058