Surface adsorption of fibronectin-derived peptide fragments: the influence of electrostatics and hydrophobicity for endothelial cells adhesion
Journal article, 2012
The adsorption on hydrophobic and hydrophilic silica-based surfaces of the integrin-binding PHSRN peptide and the single-residual-mutated analogues, PHSEN and PHSFN, is investigated by comparative QCM-D, XPS, SFG measurements and molecular dynamics calculations. Endothelial cell cultures on the peptide-functionalized materials highlight their tunable pro- or anti-angiogenic potential.
molecules
sum-frequency generation
monolayers
interfaces
Author
C. Satriano
University of Catania
M. E. Fragala
University of Catania
G. Forte
University of Catania
A. M. Santoro
Consiglo Nazionale Delle Richerche
D. La Mendola
Consiglo Nazionale Delle Richerche
Bengt Herbert Kasemo
Chalmers, Applied Physics, Chemical Physics
Soft Matter
1744-683X (ISSN) 1744-6848 (eISSN)
Vol. 8 1 53-56Subject Categories
Chemical Sciences
DOI
10.1039/c1sm06655b