Glycoprotein 130 promotes human blastocyst development in vitro
Journal article, 2013

Objective: To investigate the efficacy of leukemia inhibitory factor (LIF) and/or glycoprotein 130 Design: Laboratory study. Setting: University hospital-based IVF clinic. Patient(s): A total of 164 frozen embryos that survived thawing were cultured in media supplemented Intervention(s): Morphological development was evaluated by light microscopy. Protein expression Main Outcome Measure(s): Embryo development and protein content. Result(s): Addition of gp130 to culture media improved blastocyst formation (73% vs. 43%). Addition of Conclusion(s): Glycoprotein 130, but not LIF, seems to be beneficial for preimplantation embryo

ICMS

gp130

Blastocyst

MALDI-TOF MS

LIF

Author

F. Hambiliki

Karolinska Institutet

Jörg Hanrieder

Chalmers, Chemical and Biological Engineering, Analytical Chemistry

J. Bergquist

Uppsala University

J. Hreinsson

Uppsala University

A. Stavreus-Evers

Uppsala University

K. Wanggren

Uppsala University

Fertility and Sterility

0015-0282 (ISSN)

Vol. 99 6 1592-U444

Subject Categories

Obstetrics, Gynecology and Reproductive Medicine

DOI

10.1016/j.fertnstert.2012.12.041

More information

Latest update

5/22/2018