Induction of Laccase, Lignin Peroxidase and Manganese Peroxidase Activities in White-Rot Fungi Using Copper Complexes
Journal article, 2016

Ligninolytic enzymes, such as laccase, lignin peroxidase and manganese peroxidase, are biotechnologically-important enzymes. The ability of five white-rot fungal strains Daedaleopsis confragosa, Fomes fomentarius, Trametes gibbosa, Trametes suaveolens and Trametes versicolor to produce these enzymes has been studied. Three different copper(II) complexes have been prepared ((Him)[Cu(im)(4)(H2O)(2)](btc)center dot 3H(2)O, where im = imidazole, H(3)btc = 1,3,5-benzenetricarboxylic acid, [Cu-3(pmdien)(3)(btc)](ClO4)(3)center dot 6H(2)O) and [Cu-3(mdpta)(3)(btc)](ClO4)(3)center dot 4H(2)O, where pmdien = N,N,N',N", N"-pentamethyl-diethylenetriamine and mdpta = N,N-bis-(3-aminopropyl) methyl-amine), and their potential application for laccase and peroxidases induction have been tested. The enzyme-inducing activities of the complexes were compared with that of copper sulfate, and it has been found that all of the complexes are suitable for the induction of laccase and peroxidase activities in white-rot fungi; however, the newly-synthesized complex M1 showed the greatest potential for the induction. With respect to the different copper inducers, this parameter seems to be important for enzyme activity, which depends also on the fungal strains.


copper complex


enzymatic induction

trimesic acid


M. Vrsanska

Mendelova univerzita v Brne

S. Voberkova

Mendelova univerzita v Brne

Brno University of Technology

Vratislav Langer

Chalmers, Chemistry and Chemical Engineering, Energy and Material

D. Palovcikova

Mendelova univerzita v Brne

A. Moulick

Mendelova univerzita v Brne

Brno University of Technology

V. Adam

Mendelova univerzita v Brne

Brno University of Technology

Pavel Kopel

Mendelova univerzita v Brne

Brno University of Technology


1420-3049 (ISSN) 14203049 (eISSN)

Vol. 21 11 1553

Subject Categories

Organic Chemistry



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