Angela Beth Grommet

Assistant Professor at Chemistry and Biochemistry

The Grommet research group spans the interface between supramolecular chemistry and nanomedicine, and we are particularly interested in addressing the challenges associated with lipid nanoparticle technology. Using host-guest chemistry, we develop novel lipids and stabilizers, incorporate these components into nanoparticles, and investigate their biological activity – our aim is to reduce immunogenicity and improve cargo stability without compromising therapeutic activity. Angela Grommet has a background in coordination cages, porous liquids, and chemical reactivity under confinement.

Source: chalmers.se
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Showing 18 publications

2024

Orthogonal Phase Transfer of Oppositely Charged Fe<sup>II</sup><inf>4</inf>L<inf>6</inf> Cages

Ebba Matic, Maylis Bernard, Alexandra Jernstedt et al
Chemistry - A European Journal. Vol. In Press
Journal article
2024

Harnessing Maxwell’s demon to establish a macroscale concentration gradient

Jiratheep Pruchyathamkorn, Bao‐Nguyen T. Nguyen, Angela Beth Grommet et al
Nature Chemistry
Journal article
2023

Guest Encapsulation Alters the Thermodynamic Landscape of a Coordination Host

Hema Kuntrapakam, Angela Beth Grommet, Michał J Białek et al
Journal of the American Chemical Society. Vol. 145 (45), p. 24755-24764
Journal article
2023

Quantifying the Effect of Guest Binding on Host Environment

Hugh P. Ryan, Zachary S. Fishman, Jacob T Pawlik et al
Journal of the American Chemical Society. Vol. 145 (36), p. 19533-19541
Journal article
2021

Guest Encapsulation within Surface‐Adsorbed Self‐Assembled Cages

Hugh P. Ryan, Cally J.E. Haynes, Alyssa Smith et al
Advanced Materials. Vol. 33 (1)
Journal article
2021

Coordination Cages Selectively Transport Molecular Cargoes Across Liquid Membranes

Bao‐Nguyen T. Nguyen, John D. Thoburn, Angela Beth Grommet et al
Journal of the American Chemical Society. Vol. 143 (31), p. 12175-12180
Journal article
2020

Improving Fatigue Resistance of Dihydropyrene by Encapsulation within a Coordination Cage

Martina Canton, Angela Beth Grommet, Luca Pesce et al
Journal of the American Chemical Society. Vol. 142 (34), p. 14557-14565
Journal article
2020

Molecular Photoswitching in Confined Spaces

Angela Beth Grommet, Rafal Klajn, Lucia M. Lee
Accounts of Chemical Research. Vol. 53 (11), p. 2600-2610
Review article
2020

Heat Engine Drives Transport of an FeII4L4 Cage and Cargo

Bao‐Nguyen T. Nguyen, Angela Beth Grommet, Arnaud Tron et al
Advanced Materials. Vol. 32 (19)
Journal article
2020

Coordination Cages as Permanently Porous Ionic Liquids

Lillian Ma, Cally J.E. Haynes, Angela Beth Grommet et al
Nature Chemistry. Vol. 12 (3), p. 270-275
Journal article
2020

Molecular Factors Controlling the Isomerization of Azobenzenes in the Cavity of a Flexible Coordination Cage

Luca Pesce, Claudio Perego, Angela Beth Grommet et al
Journal of the American Chemical Society. Vol. 142 (21), p. 9792-9802
Journal article
2020

Chemical Reactivity Under Nanoconfinement

Angela Beth Grommet, Moran Feller, Rafal Klajn
Nature Nanotechnology. Vol. 15 (4), p. 256-271
Review article
2018

Orthogonal Stimuli Trigger Self-Assembly and Phase Transfer of FeII4L4 Cages and Cargoes

Anna J. McConnell, Cally J.E. Haynes, Angela Beth Grommet et al
Journal of the American Chemical Society. Vol. 140 (49), p. 16952-16956
Journal article
2018

Anion Exchange Drives Reversible Phase Transfer of Coordination Cages and their Cargoes

Angela Beth Grommet, Jack B. Hoffman, Edmundo G. Percástegui et al
Journal of the American Chemical Society. Vol. 140 (44), p. 14770-14776
Journal article
2017

Directed Phase Transfer of an FeII4L4 Cage and Encapsulated Cargo

Angela Beth Grommet, Jonathan R. Nitschke
Journal of the American Chemical Society. Vol. 139 (6), p. 2176-2179
Journal article
2017

Subcomponent Exchange Transforms an FeII4L4 Cage from High- to Low-Spin, Switching Guest Release in a Two-Cage System

Anna J. McConnell, Catherine M. Aitchison, Angela Beth Grommet et al
Journal of the American Chemical Society. Vol. 139 (18), p. 6294-6297
Journal article
2015

A triphasic sorting system: Coordination cages in ionic liquids

Angela Beth Grommet, Jeanne L. Bolliger, Colm Browne et al
Angewandte Chemie - International Edition. Vol. 127 (50), p. 15315-15319
Journal article
2011

Co-crystal screening of diclofenac

Christer Aakeröy, Angela Beth Grommet, John Desper
Pharmaceutics. Vol. 3 (3), p. 601-614
Journal article

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Showing 1 research projects

2024–2027

Bottom-up fabrication of lipid nanoparticles with low permeability

Angela Beth Grommet Chemistry and Biochemistry
Swedish Research Council (VR)

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