Michaela Wenzel
I am a microbiologist interested in antibiotic mechanisms of action and bacterial mechanisms of resistance. My group uses fluorescence and electron microscopy together with proteomic and spectroscopic techniques to study the interaction of antimicrobial compounds with bacterial cells with a focus on the bacterial cell envelope. The goal is to provide a deeper fundamental understanding of how antibiotics interact with bacterial cells and use this knowledge to develop more sustainable antibiotics and novel antibacterial strategies.
Showing 22 publications
Nature inspired unique antimicrobial peptides from Chilean marine sediments
Membrane depolarization kills dormant Bacillus subtilis cells by generating a lethal dose of ROS
Dual Action of Eeyarestatin 24 on Sec-Dependent Protein Secretion and Bacterial DNA
Roles of Bacterial Mechanosensitive Channels in Infection and Antibiotic Susceptibility
SepF supports the recruitment of the DNA translocase SftA to the Z-ring
Comparison of proteomic responses as global approach to antibiotic mechanism of action elucidation
Control of septum thickness by the curvature of SepF polymers
Do we really understand how antibiotics work?
A How-To Guide for Mode of Action Analysis of Antimicrobial Peptides
Multitarget Approaches against Multiresistant Superbugs
Membranaktive Antibiotika: neue Mechanismen gegen ein altbekanntes Ziel
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