Michaela Wenzel

Assistant Professor at Chemical Biology

Michaela Wenzel a microbiologist interested in antibiotic mechanisms of action and bacterial mechanisms of resistance. Her group uses fluorescence and electron microscopy together with proteomic and spectroscopic techniques to study the interaction of antimicrobial compounds with bacterial cells with a focus on the bacterial cell envelope. The goal is to provide a deeper fundamental understanding of how antibiotics interact with bacterial cells and use this knowledge to develop more sustainable antibiotics and novel antibacterial strategies.

Full list of publications available on Orcid.

Source: chalmers.se
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Showing 8 publications

2021

Control of septum thickness by the curvature of SepF polymers

Michaela Wenzel, Ilkay N. Celik Gulsoy, Yongqiang Gao et al
Proceedings of the National Academy of Sciences of the United States of America. Vol. 118 (2)
Journal article
2021

Comparison of proteomic responses as global approach to antibiotic mechanism of action elucidation

Christoph H.R. Senges, Jennifer J. Stepanek, Michaela Wenzel et al
Antimicrobial Agents and Chemotherapy. Vol. 65 (1)
Journal article
2021

A flat embedding method for transmission electron microscopy reveals an unknown mechanism of tetracycline

Michaela Wenzel, Marien P. Dekker, Biwen Wang et al
Communications Biology. Vol. 4 (1), p. 306-
Journal article
2020

Do we really understand how antibiotics work?

Michaela Wenzel
Future Microbiology. Vol. 15 (14)
Review article
2020

Multitarget Approaches against Multiresistant Superbugs

Declan Alan Gray, Michaela Wenzel
ACS Infectious Diseases. Vol. 6 (6), p. 1346-1365
Review article
2020

A How-To Guide for Mode of Action Analysis of Antimicrobial Peptides

Ann-Britt Schäfer, Michaela Wenzel
Frontiers in cellular and infection microbiology. Vol. 10
Review article
2020

More than a pore: A current perspective on the in vivo mode of action of the lipopeptide antibiotic daptomycin

Declan Alan Gray, Michaela Wenzel
Antibiotics. Vol. 9 (1)
Review article
2019

Membranaktive Antibiotika: neue Mechanismen gegen ein altbekanntes Ziel

Michaela Wenzel
BioSpektrum. Vol. 25 (6), p. 683-683
Journal article

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Showing 4 research projects

2021–2024

Membrane microdomains in soil bacteria

Michaela Wenzel Chemical Biology
Formas

2021–2023

Role of membrane microdomains in bacterial stress adaption and survival

Michaela Wenzel Chemical Biology
Carl Tryggers Stiftelse för Vetenskaplig Forskning

2020–2023

Antibiotic-induced amino acid release - A new antimicrobial strategy?

Michaela Wenzel Chemical Biology
Margareth Sidarta Chemical Biology
Swedish Research Council (VR)

2019–2023

Interaction of antibiotics with bacterial cells

Michaela Wenzel Chemical Biology
Ann-Britt Schäfer Chemical Biology
Chalmers

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