Michaela Wenzel
Michaela Wenzel is a microbiologist interested in antibiotic mechanisms of action and bacterial mechanisms of resistance. Her group uses fluorescence and electron microscopy together with proteomic and spectroscopic techniques to study the interaction of antimicrobial compounds with bacterial cells with a focus on the bacterial cell envelope. The goal is to provide a deeper fundamental understanding of how antibiotics interact with bacterial cells and use this knowledge to develop more sustainable antibiotics and novel antibacterial strategies. Michaela is vice director of the Center for Antibiotic Resistance Research in Gotheburg (CARe).
Showing 21 publications
Nature inspired unique antimicrobial peptides from Chilean marine sediments
Membrane depolarization kills dormant Bacillus subtilis cells by generating a lethal dose of ROS
Dual Action of Eeyarestatin 24 on Sec-Dependent Protein Secretion and Bacterial DNA
Roles of Bacterial Mechanosensitive Channels in Infection and Antibiotic Susceptibility
SepF supports the recruitment of the DNA translocase SftA to the Z-ring
Comparison of proteomic responses as global approach to antibiotic mechanism of action elucidation
Control of septum thickness by the curvature of SepF polymers
Do we really understand how antibiotics work?
A How-To Guide for Mode of Action Analysis of Antimicrobial Peptides
Multitarget Approaches against Multiresistant Superbugs
Membranaktive Antibiotika: neue Mechanismen gegen ein altbekanntes Ziel
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Showing 10 research projects
Shining light on the hidden moves: Nanoscale probing of bacterial activity
Detecting antibiotic-induced DNA damage in bacteria by single-molecule DNA microscopy
Can a membrane protein nanotrap inactivate multidrug efflux pumps?
Membrane microdomains in soil bacteria
Role of membrane microdomains in bacterial stress adaption and survival
Antibiotic-induced amino acid release - A new antimicrobial strategy?
Targeting bacterial stress responses - a new antibacterial strategy?
Nya strategier för att bryta inneboende antibiotikaresistens
Interaction of antibiotics with bacterial cells