This project will develop measurement methods for the research, development and quality control of biomolecular interfaces in diagnostic devices, and establish accurate, traceable and comparable methods to determine the amount of biomolecular probe immobilised at both planar and nanoparticle interfaces. It will also investigate novel approaches for the measurement of biointerfacial structures that can be correlated with activity and binding efficiency and methods to measure and predict the activity of immobilised probes. With the goal of supporting high throughput and multiplexed diagnostic methods BioSurf will also assess the capabilities of emerging techniques capable of detecting many targets simultaneously.
Professor vid Chalmers, Physics, Biological Physics
Teddington, United Kingdom
Funding years 2012–2014