Fredrik Höök

Professor at Chalmers University of Technology, Physics, Biological Physics

Fredrik Höök received a PhD in physics from Chalmers, Sweden, in 1997 and his research has focused on the development of surface-based bioanalytical tools, such as QCM-D, localized SPR and more recently TIRF microscopy, and their combination with microfluidics for fundamental studies of cell-membrane mimics but also for use in diagnostic and drug-screening applications. Efforts are presently focused on (i) new methods with single molecule sensitivity for studies of membrane proteins and virus infection, (ii) microfluidic platforms for cell-membrane chromatography and (iii) sophisticated surface modifications and nanofabrication schemes to facilitate improved analysis of supported cell-membrane mimics, membrane proteins and virus binding and infection. He is co-founder of Q-Sense, www.q-sense.com, who is a lead developer of QCM-D instruments. He has been awarded an Individual Grant for the Advancement of Research Leaders by the Swedish Foundation for Strategic Research in 2006 and the Göran Gustafsson prize in Physics by the Royal Swedish Society of Academy in 2012.

Source: chalmers.se

Publications

2018

Pentacyclic adenine: A versatile and exceptionally bright fluorescent DNA base analogue

Mattias Bood, Anders Foller Füchtbauer, Moa Sandberg Wranne et al
Chemical Science. Vol. 9 (14), p. 3494-3502
Journal article
2018

Nanomaterial interactions with biomembranes: Bridging the gap between soft matter models and biological context

Marco Werner, Thorsten Auth, Paul A. Beales et al
Biointerphases. Vol. 13 (2)
Journal article
2018

Nanometer-scale molecular organization in lipid membranes studied by time-of-flight secondary ion mass spectrometry

Jonas Hannestad, Fredrik Höök, Peter Sjövall
Biointerphases. Vol. 13 (3)
Journal article
2018

Antenna-Enhanced Fluorescence Correlation Spectroscopy Resolves Calcium-Mediated Lipid-Lipid Interactions

Stephan Block, Srdjan Acimovic, Nils Odebo Länk et al
ACS Nano. Vol. 12 (4), p. 3272-3279
Journal article
2017

Histo-Blood Group Antigen Presentation Is Critical for Binding of Norovirus VLP to Glycosphingolipids in Model Membranes

W. Nasir, M. Frank, Angelika Kunze et al
ACS Chemical Biology. Vol. 12 (5), p. 1288-1296
Journal article
2017

Detachment of Membrane Bound Virions by Competitive Ligand Binding Induced Receptor Depletion

Nagma Parveen, Stephan Block, Vladimir Zhdanov et al
Langmuir. Vol. 33 (16), p. 4049-4056
Journal article
2017

Single Proteoliposomes with E. coli Quinol Oxidase: Proton Pumping without Transmembrane Leaks

Johan Berg, Stephan Block, Fredrik Höök et al
Israel Journal of Chemistry. Vol. 57 (5), p. 437-445
Journal article
2017

Nanopartiklar kan förbättra avbildningsteknik och diagnostik

Bengt Herbert Kasemo, Anders Persson, Fredrik Höök
Läkartidningen. Vol. 114 (27-29)
Journal article
2017

Protein-Containing Lipid Bilayers Intercalated with Size-Matched Mesoporous Silica Thin Films

Simon Isaksson, E. B. Watkins, K. L. Browning et al
Nano Letters. Vol. 17 (1), p. 476-485
Journal article
2016

Quantification of Multivalent Interactions by Tracking Single Biological Nanoparticle Mobility on a Lipid Membrane

Stephan Block, Vladimir Zhdanov, Fredrik Höök
Nano Letters. Vol. 16 (7), p. 4382-4390
Journal article
2016

Affinity Capturing and Surface Enrichment of a Membrane Protein Embedded in a Continuous Supported Lipid Bilayer

Anders Gunnarsson, Lisa Simonsson Nyström, Sabina Burazerovic et al
ChemistryOpen. Vol. 5 (5), p. 445-449
Journal article
2016

Supported lipid bilayer repair mediated by AH peptide

M. C. Kim, Anders Gunnarsson, Seyed Tabaei et al
Physical Chemistry Chemical Physics. Vol. 18 (4), p. 3040-3047
Journal article
2016

Mucosal Vaccine Development Based on Liposome Technology

V. Bernasconi, Karin Norling, Marta Bally et al
Journal of Immunology Research
Journal article
2016

Dual-Wavelength Surface Plasmon Resonance for Determining the Size and Concentration of Sub-Populations of Extracellular Vesicles

Deborah Rupert, Ganesh V Shelke, Gustav Emilsson et al
Analytical Chemistry. Vol. 88 (20), p. 9980-9988
Journal article
2016

Nonspecific Colloidal-Type Interaction Explains Size-Dependent Specific Binding of Membrane-Targeted Nanoparticles

Anders Lundgren, Björn Agnarsson, R. Zirbs et al
ACS Nano. Vol. 10 (11), p. 9974-9982
Journal article
2016

Histo-blood group antigen presentation is critical for norovirus VLP binding to glycosphingolipids in membranes

W. Nasir, M. Frank, Angelika Kunze et al
Glycobiology. Vol. 26 (12), p. 1409-1409
Magazine article
2016

Imaging of Amyloid-β in Alzheimer’s disease transgenic mouse brains with Time-of-Flight Secondary Ion Mass Spectrometry using Immunoliposomes

Louise M Carlred, Vladana Vukojević, Björn Johansson Fast et al
Biointerphases. Vol. 11 (2), p. 1-11
Journal article
2016

Two-dimensional flow nanometry of biological nanoparticles for accurate determination of their size and emission intensity

Stephan Block, Björn Johansson Fast, Anders Lundgren et al
Nature Communications. Vol. 7, p. art no 12956 -
Journal article
2016

Kinetics of enzyme-mediated hydrolysis of lipid vesicles

Vladimir Zhdanov, Björn Agnarsson, Fredrik Höök
Chemical Physics Letters. Vol. 663, p. 51-56
Journal article
2016

Monitoring of single and double lipid membrane formation with high spatiotemporal resolution using evanescent light scattering microscopy

Björn Agnarsson, H.K. Wayment-Steele, Fredrik Höök et al
Nanoscale. Vol. 8 (46), p. 19219-19223
Journal article
2016

Hydrodynamic Propulsion of Liposomes Electrostatically Attracted to a Lipid Membrane Reveals Size-Dependent Conformational Changes

Seyed Tabaei, J. J. J. Gillissen, Stephan Block et al
ACS Nano. Vol. 10 (9), p. 8812-8820
Journal article
2015

Diffusion-limited attachment of large spherical particles to flexible membrane-immobilized receptors

Vladimir Zhdanov, Fredrik Höök
European Biophysics Journal. Vol. 44 (4), p. 219-226
Journal article
2015

Equilibrium-Fluctuation Analysis for Interaction Studies between Natural Ligands and Single G Protein-Coupled Receptors in Native Lipid Vesicles

Olov Wahlsten, Anders Gunnarsson, Lisa Simonsson Nyström et al
Langmuir. Vol. 31 (39), p. 10774-10780
Journal article
2015

Kinetics of enzymatic reactions in lipid membranes containing domains

Vladimir Zhdanov, Fredrik Höök
Physical Biology. Vol. 12 (2), p. art. no. 026003-
Journal article
2015

Strongly Stretched Protein Resistant Poly(ethylene glycol) Brushes Prepared by Grafting-To

Gustav Emilsson, Rafael L. Schoch, Laurent Feuz et al
ACS Applied Materials & Interfaces. Vol. 7 (14), p. 7505-7515
Journal article
2015

Influence of the Evanescent Field Decay Length on the Sensitivity of Plasmonic Nanodisks and Nanoholes

Francesco Mazzotta, T. W. Johnson, Andreas Dahlin et al
ACS Photonics. Vol. 2 (2), p. 256-262
Journal article
2015

Drug Discovery at the Single Molecule Level: Inhibition-in-Solution Assay of Membrane-Reconstituted beta-Secretase Using Single-Molecule Imaging

Anders Gunnarsson, Arjan Snijder, J. Hicks et al
Analytical Chemistry. Vol. 87 (8), p. 4100-4103
Journal article
2015

Neutralized Chimeric Avidin Binding at a Reference Biosensor Surface

S. Ray, R. T. Steven, F. M. Green et al
Langmuir. Vol. 31 (6), p. 1921-1930
Journal article
2015

Preserved Transmembrane Protein Mobility in Polymer-Supported Lipid Bilayers Derived from Cell Membranes

Hudson Pace, Lisa Simonsson Nyström, Anders Gunnarsson et al
Analytical Chemistry. Vol. 87 (18), p. 9194-9203
Journal article
2015

Hydrolysis of a Lipid Membrane by Single Enzyme Molecules: Accurate Determination of Kinetic Parameters.

Michael Rabe, Seyed Tabaei, Henrik Zetterberg et al
Angewandte Chemie - International Edition. Vol. 54 (3), p. 1022-1026
Journal article
2015

Assembly of RNA nanostructures on supported lipid bilayers

A. P. Dabkowska, A. Michanek, L. Jaeger et al
Nanoscale. Vol. 7 (2), p. 583-596
Journal article
2015

Evanescent Light-Scattering Microscopy for Label-Free Interfacial Imaging: From Single Sub-100 nm Vesicles to Live Cells

Björn Agnarsson, Anders Lundgren, Anders Gunnarsson et al
ACS Nano. Vol. 9 (12), p. 11849-11862
Journal article
2015

Interaction of Virus-Like Particles with Vesicles Containing Glycolipids: Kinetics of Detachment

Waqas Nasir, Marta Bally, Vladimir Zhdanov et al
Journal of Physical Chemistry B. Vol. 119 (35), p. 11466-11472
Journal article
2015

Total internal reflection fluorescence microscopy for determination of size of individual immobilized vesicles: Theory and experiment

Thomas Olsson, Vladimir Zhdanov, Fredrik Höök
Journal of Applied Physics. Vol. 118 (6)
Journal article
2015

Design of Surface Modifications for Nanoscale Sensor Applications

E. Reimhult, Fredrik Höök
Sensors. Vol. 15 (1), p. 1635-1675
Journal article
2014

Optical waveguide-based single-molecule studies for medical diagnostics and drug screening applications

Björn Agnarsson, Fredrik Höök
Latin America Optics and Photonics Conference, LAOP 2014, Cancun, Mexico, 16-21 November 2014
Paper in proceedings
2014

Plasmon-enhanced four-wave mixing by nanoholes in thin gold films

Henning Hagman, Olof Bäcke, Juris Kiskis et al
Optics Letters. Vol. 39 (4), p. 1001-1004
Journal article
2014

Optical waveguide-based single-molecule studies in diagnostics and drug screening

Fredrik Höök
Optical Sensors, 2014, Barcelona, Spain, 27-31 July 2014
Conference contribution
2014

Plasmonic Nanopores in Metal-Insulator-Metal Films

Andreas Dahlin, Mokhtar Mapar, Kunli Xiong et al
Advanced Optical Materials. Vol. 2 (6), p. 556-564
Journal article
2014

Determination of exosome concentration in solution using surface plasmon resonance spectroscopy.

Deborah Rupert, Cecilia Lässer, Maria Eldh et al
Analytical Chemistry. Vol. 86 (12), p. 5929-5936
Journal article
2014

Simultaneous imaging of amyloid-β and lipids in brain tissue using antibody-coupled liposomes and time-of-flight secondary ion mass spectrometry

Louise M Carlred, Anders Gunnarsson, S. Solé-Domènech et al
Journal of the American Chemical Society. Vol. 136 (28), p. 9973-9981
Journal article
2014

Label-Free Measurements of the Diffusivity of Molecules in Lipid Membranes

Björn Johansson Fast, Fredrik Höök, D. Klenerman et al
ChemPhysChem. Vol. 15 (3), p. 486-491
Journal article
2014

Liposome binding for multiplexed biomolecule detection and imaging using ToF-SIMS

Peter Sjövall, Björn Agnarsson, Louise M Carlred et al
Surface and Interface Analysis. Vol. 46 (10-11), p. 707-711
Journal article
2013

Equilibrium-fluctuation-analysis of single liposome binding events reveals how cholesterol and Ca2+ modulate glycosphingolipid trans-interactions

Angelika Kunze, Marta Bally, Fredrik Höök et al
Scientific Reports. Vol. 3
Journal article
2013

A virus biosensor with single virus-particle sensitivity based on fluorescent vesicle labels and equilibrium fluctuation analysis

Marta Bally, Mauritz Graule, F. Parra et al
Biointerphases. Vol. 8, p. Article number: 4-
Journal article
2013

Nucleation in mesoscopic systems under transient conditions: Peptide-induced pore formation in vesicles

Vladimir Zhdanov, Fredrik Höök
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. Vol. 87 (4)
Journal article
2013

Promises and challenges of nanoplasmonic devices for refractometric biosensing

Andreas Dahlin, N. J. Wittenberg, Fredrik Höök et al
Nanophotonics. Vol. 2 (2), p. 83-101
Journal article
2013

A Secretory Artificial Cell for Exocytosis

Ann-Sofie Cans, Lisa Simonsson Nyström, Michael Kurczy et al
Biophysical Journal. Vol. 104 (2 Suppl 1), p. 621A-622A
Conference poster
2013

Single lipid vesicle assay for characterizing single-enzyme kinetics of phospholipid hydrolysis in a complex biological fluid.

Seyed Tabaei, Michael Rabe, Henrik Zetterberg et al
Journal of the American Chemical Society. Vol. 135 (38), p. 14151-8
Journal article
2013

Hydrodynamic separation of proteins in supported lipid bilayers confined by gold barriers

Björn Johansson Fast, Thomas Olsson, Peter Jönsson et al
Soft Matter. Vol. 9 (39), p. 9414-9419
Journal article
2012

Formation and Diffusivity Characterization of Supported Lipid Bilayers with Complex Lipid Compositions

Lisa Simonsson Nyström, Fredrik Höök
Langmuir. Vol. 28 (28), p. 10528-10533
Journal article
2012

Design of Intelligent Surface Modifications and Optimal Liquid Handling for Nanoscale Bioanalytical Sensors

Laurent Feuz, Fredrik Höök, E. Reimhult
Intelligent Surfaces in Biotechnology: Scientific and Engineering Concepts, Enabling Technologies, and Translation to Bio-Oriented Applications, p. 71-122
Book chapter
2012

Solute transport on the sub 100 ms scale across the lipid bilayer membrane of individual proteoliposomes

Gabriel Ohlsson, Seyed Tabaei, J. P. Beech et al
Lab on a Chip - Miniaturisation for Chemistry and Biology. Vol. 12 (22), p. 4635-4643
Journal article
2012

Time-Resolved Surface-Enhanced Ellipsometric Contrast Imaging for Label-Free Analysis of Biomolecular Recognition Reactions on Glycolipid Domains

Anders Gunnarsson, Marta Bally, Peter Jönsson et al
Analytical Chemistry. Vol. 84 (15), p. 6538-6545
Journal article
2012

Kinetics of the enzyme-vesicle interaction including the formation of rafts and membrane strain

Vladimir Zhdanov, Fredrik Höök
Biophysical Chemistry. Vol. 170, p. 17-24
Journal article
2012

Nanoplasmonic sensing combined with artificial cell membranes

Magnus Jonsson, Andreas Dahlin, Fredrik Höök
, p. 59-82
Book
2012

Interaction of virions with membrane glycolipids

Marta Bally, Kristian Dimitrievski, Göran Larson et al
Physical Biology. Vol. 9 (2), p. Article Number: 026011-
Journal article
2012

A functioning artificial secretory cell

Lisa Simonsson Nyström, Michael Kurczy, R. Trouillon et al
Scientific Reports. Vol. 2, p. no. 824-
Journal article
2012

Material-Selective Surface Chemistry for Nanoplasmonic Sensors: Optimizing Sensitivity and Controlling Binding to Local Hot Spots

Laurent Feuz, Magnus Jonsson, Fredrik Höök
Nano Letters. Vol. 12 (2), p. 873-879
Journal article
2012

Norovirus GII.4 Virus-like Particles Recognize Galactosylceramides in Domains of Planar Supported Lipid Bilayers.

Marta Bally, Gustaf E Rydell, Raphael Zahn et al
Angewandte Chemie - International Edition. Vol. 51 (48), p. 12020-4
Journal article
2012

High throughput fabrication of plasmonic nanostructures in nanofluidic pores for biosensing applications

Francesco Mazzotta, Fredrik Höök, Magnus Jonsson
Nanotechnology. Vol. 23 (41)
Journal article
2012

Single Vesicle Analysis Reveals Nanoscale Membrane Curvature Selective Pore Formation in Lipid Membranes by an Antiviral α-Helical Peptide

Seyed Tabaei, Michael Rabe, Vladimir Zhdanov et al
Nano Letters. Vol. 12 (11), p. 5719-5725
Journal article
2011

Continuous Lipid Bilayers Derived from Cell Membranes for Spatial Molecular Manipulation

Lisa Simonsson Nyström, Anders Gunnarsson, Patric Wallin et al
Journal of the American Chemical Society. Vol. 133 (35), p. 14027-14032
Journal article
2011

Resonance-Mode Electrochemical Impedance Measurements of Silicon Dioxide Supported Lipid Bilayer Formation and Ion Channel Mediated Charge Transport

A. Lundgren, J. Hedlund, O. Andersson et al
Analytical Chemistry. Vol. 83 (20), p. 7800-7806
Journal article
2011

Accumulation and Separation of Membrane-Bound Proteins Using Hydrodynamic Forces

Peter Jönsson, Anders Gunnarsson, Fredrik Höök
Analytical Chemistry. Vol. 83 (2), p. 604-611
Journal article
2011

Phase transitions in adsorbed lipid vesicles measured using a quartz crystal microbalance with dissipation monitoring

Gabriel Ohlsson, ANNA KATARINA TIGERSTRÖM, Fredrik Höök et al
Soft Matter. Vol. 7 (22), p. 10749-10755
Journal article
2011

Kinetics of Ligand Binding to Membrane Receptors from Equilibrium Fluctuation Analysis of Single Binding Events

Anders Gunnarsson, L. Dexlin, Patric Wallin et al
Journal of the American Chemical Society. Vol. 133 (38), p. 14852-14855
Journal article
2011

Effects of Surface Pressure and Internal Friction on the Dynamics of Shear-Driven Supported Lipid Bilayers

Peter Jönsson, Fredrik Höök
Langmuir. Vol. 27 (4), p. 1430-1439
Journal article
2011

Interaction of Single Viruslike Particles with Vesicles Containing Glycosphingolipids

Marta Bally, Anders Gunnarsson, L. Svensson et al
Physical Review Letters. Vol. 107 (18)
Journal article
2010

Spatial-Resolution Limits in Mass Spectrometry Imaging of Supported Lipid Bilayers and Individual Lipid Vesicles

Anders Gunnarsson, F. Kollmer, S. Sohn et al
Analytical Chemistry. Vol. 82 (6), p. 2426-2433
Journal article
2010

Liposome-Based Chemical Barcodes for Single Molecule DNA Detection Using Imaging Mass Spectrometry

Anders Gunnarsson, Peter Sjövall, Fredrik Höök
Nano Letters. Vol. 10 (2), p. 732-737
Journal article
2010

Detecting water transport through lipid membranes on a millisecond level using microfluidics and fluorescent dyes

Gabriel Ohlsson, Seyed Tabaei, Magnus Brändén et al
European Cells and Materials. Vol. 20 (suppl. 3), p. 191-
Journal article
2010

Refractive-Index-Based Screening of Membrane-Protein-Mediated Transfer across Biological Membranes

Magnus Brändén, Seyed Tabaei, Gerhard Fischer et al
Biophysical Journal. Vol. 99 (1), p. 124-133
Journal article
2010

Heavy Meromyosin Molecules Extending More Than 50 nm above Adsorbing Electronegative Surfaces

M. Persson, N. Albet-Torres, L. Ionov et al
Langmuir. Vol. 26 (12), p. 9927-9936
Journal article
2010

Investigation of Adsorption and Cross-Linking of a Mussel Adhesive Protein Using Attenuated Total Internal Reflection Fourier Transform Infrared Spectroscopy (ATR-FTIR)

Camilla Fant, J. Hedlund, Fredrik Höök et al
Journal of Adhesion. Vol. 86 (1), p. 25-38
Journal article
2010

Locally Functionalized Short-Range Ordered Nanoplasmonic Pores for Bioanalytical Sensing

Magnus Jonsson, Andreas Dahlin, Laurent Feuz et al
Analytical Chemistry. Vol. 82 (5), p. 2087-2094
Journal article
2010

RNA and DNA interactions with zwitterionic and charged lipid membranes - A DSC and QCM-D study

A. Michanek, N. Kristen, Fredrik Höök et al
Biochimica et Biophysica Acta - Biomembranes. Vol. 1798 (4), p. 829-838
Journal article
2010

Probing molecular recognition on the single molecule level

Anders Gunnarsson, Peter Jönsson, Peter Sjövall et al
European Cells and Materials. Vol. 20 (suppl. 3), p. 97-
Paper in proceedings
2010

High-Performance Biosensing Using Arrays of Plasmonic Nanotubes

J. McPhillips, A. Murphy, Magnus Jonsson et al
ACS Nano. Vol. 4 (4), p. 2210-2216
Journal article
2010

Improving the Limit of Detection of Nanoscale Sensors by Directed Binding to High-Sensitivity Areas

Laurent Feuz, Peter Jönsson, Magnus Jonsson et al
ACS Nano. Vol. 4 (4), p. 2167-2177
Journal article
2010

Nanoplasmonic biosensing with on-chip electrical detection

Francesco Mazzotta, Guoliang Wang, Carl Hägglund et al
Biosensors and Bioelectronics. Vol. 26 (4), p. 1131-1136
Paper in proceedings
2010

DNA Binding to Zwitterionic Model Membranes

M. L. Ainalem, N. Kristen, K. J. Edler et al
Langmuir. Vol. 26 (7), p. 4965-4976
Journal article
2010

Quartz crystal microbalance with dissipation monitoring of supported lipid bilayers on various substrates

N. J. Cho, C. W. Frank, Bengt Herbert Kasemo et al
Nature Protocols. Vol. 5 (6), p. 1096-1106
Journal article
2010

Simulation of dissociation of DNA duplexes attached to the surface

Vladimir Zhdanov, Anders Gunnarsson, Fredrik Höök
Central European Journal of Physics. Vol. 8 (6), p. 883-892
Magazine article
2010

Molecular motors on lipid bilayers and silicon dioxide: different driving forces for adsorption

N. Albet-Torres, Anders Gunnarsson, M. Persson et al
Soft Matter. Vol. 6 (14), p. 3211-3219
Journal article
2010

Site-Specific DNA-Controlled Fusion of Single Lipid Vesicles to Supported Lipid Bilayers

Lisa Simonsson Nyström, Peter Jönsson, Gudrun Stengel et al
ChemPhysChem. Vol. 11 (5), p. 1011-1017
Journal article
2010

Sealing of Submicrometer Wells by a Shear-Driven Lipid Bilayer

Peter Jönsson, Magnus Jonsson, Fredrik Höök
Nano Letters. Vol. 10 (5), p. 1900-1906
Journal article
2010

Shear-driven motion of supported lipid bilayers in microfluidic channels

Peter Jönsson, Magnus Jonsson, J. P. Beech et al
European Cells and Materials. Vol. 20 (suppl. 3), p. 126-
Paper in proceedings
2010

A simple nanoplasmonic sensor with microliter sample handling

Laurent Feuz, Hossein Agheli, Anders Gunnarsson et al
European Cells and Materials. Vol. 20 (suppl. 3), p. 81-
Paper in proceedings
2009

Mechanical Behavior of a Supported Lipid Bilayer under External Shear Forces

Peter Jönsson, J. P. Beech, J. O. Tegenfeldt et al
Langmuir. Vol. 25 (11), p. 6279-6286
Journal article
2009

Alpha-Helical Peptide-Induced Vesicle Rupture Revealing New Insight into the Vesicle Fusion Process As Monitored in Situ by Quartz Crystal Microbalance-Dissipation and Reflectometry

N. J. Cho, Guoliang Wang, Malin Edvardsson et al
Analytical Chemistry. Vol. 81 (12), p. 4752-4761
Journal article
2009

High-resolution microspectroscopy pf plasmonic nanostructures for miniaturized biosensing

Andreas Dahlin, Si Chen, Magnus Jonsson et al
Analytical Chemistry. Vol. 81 (16), p. 6572-6580
Journal article
2009

Kinetic and thermodynamic characterization of single-mismatch discrimination using single-molecule imaging

Anders Gunnarsson, Peter Jönsson, Vladimir Zhdanov et al
Nucleic Acids Research. Vol. 37 (14), p. e99 (art no)-
Journal article
2009

Self-assembly formation of multiple DNA-tethered lipid bilayers

Seyed Tabaei, Peter Jönsson, Magnus Brändén et al
Journal of Structural Biology. Vol. 168 (1), p. 200-206
Journal article
2009

Shear-Driven Motion of Supported Lipid Bilayers in Microfluidic Channels

Peter Jönsson, J. P. Beech, J. O. Tegenfeldt et al
Journal of the American Chemical Society. Vol. 131 (14), p. 5294-5297
Journal article
2009

Rupture Pathway of Phosphatidylcholine Liposomes on Silicon Dioxide

Erik Reimhult, Bengt Herbert Kasemo, Fredrik Höök
International Journal of Molecular Sciences. Vol. 10 (4)
Journal article
2009

QCM-D studies of human norovirus VLPs binding to glycosphingolipids in supported lipid bilayers reveal strain-specific characteristics.

Gustaf E Rydell, Andreas Dahlin, Fredrik Höök et al
Glycobiology. Vol. 19 (11), p. 1176-84
Journal article
2008

Quantitative Biological Surface Science: Challenges and Recent Advances

Fredrik Höök, Bengt Herbert Kasemo, M. Grunze et al
ACS Nano. Vol. 2 (12), p. 2428-2436
Journal article
2008

Addressable adsorption of lipid vesicles and subsequent protein interaction studies

G. Klenkar, Björn Brian, T. Ederth et al
Biointerphases. Vol. 3 (2), p. 29-37
Journal article
2008

Nanoplasmonic biosensing with focus on short-range ordered nanoholes in thin metal films

Magnus Jonsson, Andreas Dahlin, Peter Jönsson et al
Biointerphases. Vol. 3 (3), p. FD30-FD40
Journal article
2008

Label-Free Measurements of Molecular Transport across Liposome Membranes using Evanescent-Wave Sensing

Magnus Brändén, S. Dahlin, Fredrik Höök
ChemPhysChem. Vol. 9 (17), p. 2480-2485
Journal article
2008

A combined reflectometry and quartz crystal microbalance with dissipation setup for surface interaction studies

G Wang, Michael Rodahl, Malin Edvardsson et al
Review of Scientific Instruments. Vol. 79 (7), p. 075107-
Journal article
2007

Supported lipid bilayers, tethered lipid vesicles, and vesicle fusion investigated using gravimetric, plasmonic, and microscopy techniques

Fredrik Höök, Gudrun Stengel, Andreas Dahlin et al
Biointerphases. Vol. 3 (2)
Journal article
2007

Controlled radial distribution of nanoscale vesicles during binding to an oscillating QCM surface

Malin Edvardsson, Vladimir Zhdanov, Fredrik Höök
Small. Vol. 3, p. 585-589
Journal article
2007

Characterization of a proton pumping transmembrane protein incorporated into a supported three-dimensional matrix of proteoliposomes

Annette Graneli, Jason J. Benkoski, Fredrik Höök
Analytical Biochemistry. Vol. 367 (1), p. 87-94
Journal article
2006

Light-Regulated release of liposomes from phospholipid membranes via photoresponsive polymer-DNA conjugates

Jason J. Benkoski, Aldo Jesorka, Malin Edvardsson et al
Soft Matter. Vol. 2 (8), p. 710-715
Journal article
2006

Suppression of binding events via external perturbation with emphasis on QCM

Vladimir Zhdanov, Malin Edvardsson, Fredrik Höök et al
Chemical Physics Letters. Vol. 424 (1-3), p. 214-217
Journal article
2006

Investigation of binding event perturbations caused by elevated QCM-D oscillation amplitude

Malin Edvardsson, Michael Rodahl, Fredrik Höök
The Analyst. Vol. 131 (7), p. 822-828
Journal article
2006

A multitechnique study of liposome adsorption an Au and I ipid bilayer formation on SiO2

Erik Reimhult, Michael Zäch, Fredrik Höök et al
Langmuir. Vol. 22 (7), p. 3313-3319
Journal article
2006

Quantification of Oligonucleotide Modifications of Small Unilamellar Lipid Vesicles

Indriati Pfeiffer, Fredrik Höök
Analytical Chemistry. Vol. 78 (21), p. 7493-7498
Journal article
2005

Light-activated desorption of photoactive polyelectrolytes from supported lipid bilayers

Jason J. Benkoski, A. Jesorka, Bengt Herbert Kasemo et al
Macromolecules. Vol. 38 (9), p. 3852-3860
Journal article
2005

Gravimetric antigen detection utilizing anitbody-modified lipid bilayers

Charlotte Larsson, Hanna Bramfeldt, Christer Wingren et al
Analytical Biochemistry. Vol. 345 (1), p. 72-80
Journal article
2005

A dual-frequency QCM-D setup operating at elevated oscillation amplitudes

Malin Edvardsson, Mikael Rodahl, Bengt Herbert Kasemo et al
Analytical Chemistry. Vol. 77 (15), p. 4918-4926
Journal article
2005

Plasmonic Sensing Characteristics o f Single Nanometric Holes

Tomas Rindzevicius, Y. Alaverdyan, A. Dahlin et al
Nano Letters. Vol. 5 (11), p. 2335-2339
Journal article
2005

Lateral mobility of tethered vesicle - DNA assemblies

Jason J. Benkoski, Fredrik Höök
Journal of Physical Chemistry B. Vol. 109 (19), p. 9773-9779
Journal article
2005

Localized surface plasmon sensing of lipid-membrane-mediated biorecognition events

Andreas Dahlin, Michael Zäch, Tomas Rindzevicius et al
Journal of the American Chemical Society. Vol. 127 (14), p. 5043-5048
Journal article
2004

DNA-based formation of a supported, three-dimensional lipid vesicle matrix probed by QCM-D and SPR

Annette Granéli, Malin Edvardsson, Fredrik Höök
Chem. Phys. Chem.. Vol. 5 (5), p. 729-733
Journal article
2004

Utilizing adsorbed proteoliposomes trapped in a non-ruptured state on SiO2 for amplified detection of membrane proteins

Annette Granéli, Jan Rydström, Bengt Herbert Kasemo et al
Biosensors and Bioelectronics. Vol. 20 (3), p. 498-504
Journal article
2004

Bivalent Cholesterol-based coupling of oligonucleotides to lipid membrane assemblies

Indriati Pfeiffer, Fredrik Höök
Journal of the American Chemical Society. Vol. 126 (33), p. 10224-10225
Journal article
2004

Micropatterening of DNA-tagged visicles

Brigitte Stadler, Didier Falconnet, Indriati Pfeiffer et al
Langmuir. Vol. 20 (26), p. 11348-11354
Journal article
2003

Formation of Supported Lipid Bilayer Membranes on SiO2 from Proteoliposomes Containing Transmembrane Proteins

Annette Graneli, Jan Rydström, Bengt Herbert Kasemo et al
Langmuir. Vol. 19, p. 842-850
Journal article
2001

Measurement of the Dynamics of Exocytosis and Vesicle Retrieval at Cell Populations using a Quartz Crystal Microbalance

Ann-Sofie Cans, Fredrik Höök, Oleg Shupliakov et al
Analytical Chemistry. Vol. 73, p. 5805-5811
Journal article
2001

Formation of protein-containing supported lipid bilayers on SiO2

Annette Graneli, Fredrik Höök, Jan Rydström et al
Biophysical Journal. Vol. 80 (1 (part 2)), p. 258a-258a (meeting abstract 1051)
Paper in proceedings
2001

Characterization of PNA and DNA Immobilization and Subsequent Hybridization with DNA Using Acoustic-Shear-Wave Attenuation Measurements

Fredrik Höök, Arghya Ray, Bengt Nordén et al
Langmuir. Vol. 17 (26), p. 8305-8312
Journal article
2000

Functional surfaces for biorecognition and sensing

Fredrik Höök, Karin Glasmästar, Annette Graneli et al
Abstract of Papers of the American Chemical Society. Vol. 220, p. U257-U257
Paper in proceedings
2000

Adsorption behavior and enzymatically or chemically induced cross-linking of a mussel adhesive protein

Kristin Sott, H. Elwing, Fredrik Höök
Biofouling. Vol. 16 (2-4), p. 119-132
Journal article

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Projects

2017–2024

Funktionell leverans av nukleotid-baserade läkemedel

Fredrik Höök Biological Physics
Marcus Wilhelmsson Chemistry and Biochemistry
Elin Esbjörner Winters Chemical Biology
Swedish Foundation for Strategic Research (SSF)

2013–2018

Plasmonic antennas shine light on the nanoworld

Mikael Käll Bionanophotonics
Kasper Moth-Poulsen Polymer Technology
Fredrik Höök Biological Physics
Eva Olsson Eva Olsson Group
Peter Johansson Bionanophotonics
Andreas Dahlin Applied Chemistry
Christoph Langhammer Chemical Physics
Alexander Dmitriev Bionanophotonics
Knut and Alice Wallenberg Foundation

2012–2017

Funktionella elektromagnetiska metamaterial & optisk sensing

Mikael Käll Bionanophotonics
Alexander Dmitriev Bionanophotonics
Christoph Langhammer Chemical Physics
Andreas Dahlin Applied Chemistry
Fredrik Höök Biological Physics
Swedish Foundation for Strategic Research (SSF)

2016–2019

Design of porus lipid-silica nanocarriers for local enzyme-controlled drug administration

Fredrik Höök Biological Physics
Hanna Gustafsson Biological Physics
ÅForsk (Ångpanneföreningens Foundation for Research and Development)

2013–2015

System för analys av läkemedel mot membranbundna receptorer

Fredrik Höök Biological Physics
VINNOVA

2012–2017

Organiska bioelektroniska ytor för membrankromatografi

Fredrik Höök Biological Physics
Swedish Foundation for Strategic Research (SSF)

2012–2014

BioSurf

Fredrik Höök Biological Physics
European Association of National Metrology Institutes (EURAMET)

2015–2018

Surface-sensitive microscopy for studies of cellular membranes

Fredrik Höök Biological Physics
Swedish Research Council (VR)

There might be more projects where Fredrik Höök participates, but you have to be logged in as a Chalmers employee to see them.