Nanoplasmonic biosensing with on-chip electrical detection
Paper in proceedings, 2010

A nanoplasmonic biosensor chip with integrated electrical detection is presented. The concept is based on the local refractive index sensitivity of nanoplasmonic gold nanodisks (110 nm in diameter and 20 nm in height) that are fabricated, through a parallel method, directly on an array of silicon solar cells or photoactive diodes. The nanoplasmonic properties of the sensor chip were investigated both optically and electrically, with excellent agreement between the two. We show that local changes in the refractive index of the surrounding environment gives changes in the nanoplasmonic properties of the gold nanodisks, which induce corresponding changes in the photocurrent at single wavelengths of the nanoplasmonic solar cells. With a simple light-emitting diode as light source, and together with a material-specific modification protocol, the photocurrent output of the nanoplasmonic sensor chip was successfully used to monitor a specific biorecognition reaction in real-time.

Nanodisks

Localized surface plasmon resonance

Bioanalytical sensing

Photo diode

Biosensor

Solar cell

Author

Francesco Mazzotta

Chalmers, Applied Physics, Biological Physics

Guoliang Wang

Chalmers, Applied Physics, Biological Physics

Carl Hägglund

Chalmers, Applied Physics, Chemical Physics

Fredrik Höök

Chalmers, Applied Physics, Biological Physics

Magnus Jonsson

Chalmers, Applied Physics, Biological Physics

Biosensors and Bioelectronics

0956-5663 (ISSN)

Vol. 26 4 1131-1136

Areas of Advance

Nanoscience and Nanotechnology (2010-2017)

Life Science Engineering (2010-2018)

Subject Categories

Industrial Biotechnology

Analytical Chemistry

DOI

10.1016/j.bios.2010.07.008

More information

Created

10/7/2017