High-Performance Biosensing Using Arrays of Plasmonic Nanotubes
Journal article, 2010

We show that aligned gold nanotube arrays capable of supporting plasmonic resonances can be used as high performance refractive index sensors in biomolecular binding reactions. A methodology to examine the sensing ability of the inside and outside walls of the nanotube structures is presented. The sensitivity of the plasmonic nanotubes is found to increase as the nanotube walls are exposed, and the sensing characteristic of the inside and outside walls is shown to be different. Finite element simulations showed good qualitative agreement with the observed behavior. Free standing gold nanotubes displayed bulk sensitivities in the region of 250 nm per refractive index unit and a signal-to-noise ratio better than 1000 upon protein binding which is highly competitive with state-of-the-art label-free sensors.

gold nanotubes

label-free biosensing

array

GROWTH

plasmonic

SINGLE

metamaterial

ELECTRODEPOSITION

NANORODS

GOLD

POLYPYRROLE

COLLOIDAL LITHOGRAPHY

LSPR

SENSORS

RESONANCE

finite element simulation

SENSITIVITY

Author

J. McPhillips

Queen's University Belfast

A. Murphy

Queen's University Belfast

Magnus Jonsson

Chalmers, Applied Physics, Biological Physics

W. R. Hendren

Queen's University Belfast

R. Atkinson

Queen's University Belfast

Fredrik Höök

Chalmers, Applied Physics, Biological Physics

A. V. Zayats

Queen's University Belfast

R. J. Pollard

Queen's University Belfast

ACS Nano

1936-0851 (ISSN) 1936-086X (eISSN)

Vol. 4 4 2210-2216

Subject Categories

Biophysics

DOI

10.1021/nn9015828

More information

Latest update

5/14/2018