Assessment of fracture risk.
Journal article, 2005
The diagnosis of osteoporosis is based on the measurement of bone mineral density (BMD). There are a number of clinical risk factors that provide information on fracture risk over and above that given by BMD. The assessment of fracture risk thus needs to be distinguished from diagnosis to take account of the independent value of the clinical risk factors. These include age, a prior fragility fracture, a parental history of hip fracture, smoking, use of systemic corticosteroids, excess alcohol intake and rheumatoid arthritis. The independent contribution of these risk factors can be integrated by the calculation of fracture probability with or without the use of BMD. Treatment can then be offered to those identified to have a fracture probability greater than an intervention threshold.
therapeutic use
Female
Glucocorticoids
Arthritis
Male
Risk Assessment
Recurrence
complications
drug therapy
Smoking
adverse effects
Adult
etiology
diagnosis
Aged
Bone
Rheumatoid
Alcohol Drinking
Age Factors
genetics
Fractures
Middle Aged
complications
genetics
adverse effects
Humans
Osteoporosis
Author
John A Kanis
Frederik Borgstrom
Chris De Laet
Helena Johansson
University of Gothenburg
Olof Johnell
Bengt Jonsson
Anders Odén
Chalmers, Mathematical Sciences, Mathematical Statistics
University of Gothenburg
Niklas Zethraeus
Bruce Pfleger
Nikolai Khaltaev
Osteoporosis International
0937-941X (ISSN) 1433-2965 (eISSN)
Vol. 16 6 581-9Subject Categories
Endocrinology and Diabetes
Physiology
DOI
10.1007/s00198-004-1780-5
PubMed
15616758