Assessment of fracture risk.
Artikel i vetenskaplig tidskrift, 2005

The diagnosis of osteoporosis is based on the measurement of bone mineral density (BMD). There are a number of clinical risk factors that provide information on fracture risk over and above that given by BMD. The assessment of fracture risk thus needs to be distinguished from diagnosis to take account of the independent value of the clinical risk factors. These include age, a prior fragility fracture, a parental history of hip fracture, smoking, use of systemic corticosteroids, excess alcohol intake and rheumatoid arthritis. The independent contribution of these risk factors can be integrated by the calculation of fracture probability with or without the use of BMD. Treatment can then be offered to those identified to have a fracture probability greater than an intervention threshold.

therapeutic use

Female

Glucocorticoids

Arthritis

Male

Risk Assessment

Recurrence

complications

drug therapy

Smoking

adverse effects

Adult

etiology

diagnosis

Aged

Bone

Rheumatoid

Alcohol Drinking

Age Factors

genetics

Fractures

Middle Aged

complications

genetics

adverse effects

Humans

Osteoporosis

Författare

John A Kanis

Frederik Borgstrom

Chris De Laet

Helena Johansson

Göteborgs universitet

Olof Johnell

Bengt Jonsson

Anders Odén

Chalmers, Matematiska vetenskaper, matematisk statistik

Göteborgs universitet

Niklas Zethraeus

Bruce Pfleger

Nikolai Khaltaev

Osteoporosis International

0937-941X (ISSN) 1433-2965 (eISSN)

Vol. 16 581-9

Ämneskategorier

Endokrinologi och diabetes

Fysiologi

DOI

10.1007/s00198-004-1780-5

PubMed

15616758