Photoswitched DNA-binding of a photochromic spiropyran
Journal article, 2008

The dramatically different DNA-binding properties of the two isomeric forms of a photochromic spiropyran have been demonstrated, enabling photoswitched DNA binding. The closed, UV-absorbing form shows no signs of interaction with DNA. Upon UV exposure the spiropyran is isomerized to the open form that binds to DNA by intercalation. The process is fully reversible as the corresponding dissociation process is induced by visible light. Copyright © 2008 American Chemical Society.

Author

Johanna Andersson

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Shiming Li

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Per Lincoln

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Joakim Andreasson

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Journal of the American Chemical Society

0002-7863 (ISSN) 1520-5126 (eISSN)

Vol. 130 36 11836-11837

Subject Categories

Chemical Sciences

DOI

10.1021/ja801968f

More information

Created

10/8/2017