Methylene blue intercalates with triplex poly(dT)*poly(dA)┬Ěpoly(dT) but not duplex poly(dA)┬Ěpoly(dT)
Journal article, 1995

Methylene blue intercalates with tripler poly(dT*dA.dT) even though it binds to the precursor duplex poly(dA.dT) in the major groove; the switch may be related to conformational modifications of the polynucleotide structure upon binding of the third strand.

spectroscopy

helix-specific ligands

antisense

ethidium-bromide

dna triplex

groove binding-drug

recognition

oligonucleotides

nucleic-acids

complex

Author

Eimer Tuite

Department of Physical Chemistry

Bengt Nordén

Department of Physical Chemistry

Journal of the Chemical Society - Series Chemical Communications

0022-4936 (ISSN)

1 53-54

Subject Categories

Chemical Sciences

DOI

10.1039/c39950000053

More information

Created

10/6/2017