Methylene blue intercalates with triplex poly(dT)*poly(dA)·poly(dT) but not duplex poly(dA)·poly(dT)
Artikel i vetenskaplig tidskrift, 1995
Methylene blue intercalates with tripler poly(dT*dA.dT) even though it binds to the precursor duplex poly(dA.dT) in the major groove; the switch may be related to conformational modifications of the polynucleotide structure upon binding of the third strand.
spectroscopy
helix-specific ligands
antisense
ethidium-bromide
dna triplex
groove binding-drug
recognition
oligonucleotides
nucleic-acids
complex
Författare
Eimer Tuite
Institutionen för fysikalisk kemi
Bengt Nordén
Institutionen för fysikalisk kemi
Journal of the Chemical Society - Series Chemical Communications
0022-4936 (ISSN)
1 53-54Ämneskategorier
Kemi
DOI
10.1039/c39950000053