Bacterial cellulose-based materials and medical devices: current state and perspectives
Journal article, 2011
Bacterial cellulose (BC) is a unique and promising material for use as implants and scaffolds in tissue engineering. It is composed of a pure cellulose nanofiber mesh spun by bacteria. It is remarkable for its strength and its ability to be engineered structurally and chemically at nano-, micro-, and macroscales. Its high water content and purity make the material biocompatible for multiple medical applications. Its biocompatibility, mechanical strength, chemical and morphologic controllability make it a natural choice for use in the body in biomedical devices with broader application than has yet been utilized. This paper reviews the current state of understanding of bacterial cellulose, known methods for controlling its physical and chemical structure (e.g., porosity, fiber alignment, etc.), biomedical applications for which it is currently being used, or investigated for use, challenges yet to be overcome, and future possibilities for BC.
p253
proliferation
tissue
abdominal-wall
Bacterial cellulose
microbial cellulose
bone
biomimetic synthesis
Nanocellulose
Biocompatibility
ntana jd
1990
scaffolds
Acetobacter xylinum
Microbial cellulose
biomedical applications
Biomedical
v24-5
biocompatibility
agitated culture
Author
N. Petersen
University of Virginia
Paul Gatenholm
Chalmers, Chemical and Biological Engineering, Polymer Technology
Applied Microbiology and Biotechnology
0175-7598 (ISSN) 1432-0614 (eISSN)
Vol. 91 5 1277-1286Subject Categories
Chemical Sciences
DOI
10.1007/s00253-011-3432-y