Bacterial cellulose-based materials and medical devices: current state and perspectives
Artikel i vetenskaplig tidskrift, 2011

Bacterial cellulose (BC) is a unique and promising material for use as implants and scaffolds in tissue engineering. It is composed of a pure cellulose nanofiber mesh spun by bacteria. It is remarkable for its strength and its ability to be engineered structurally and chemically at nano-, micro-, and macroscales. Its high water content and purity make the material biocompatible for multiple medical applications. Its biocompatibility, mechanical strength, chemical and morphologic controllability make it a natural choice for use in the body in biomedical devices with broader application than has yet been utilized. This paper reviews the current state of understanding of bacterial cellulose, known methods for controlling its physical and chemical structure (e.g., porosity, fiber alignment, etc.), biomedical applications for which it is currently being used, or investigated for use, challenges yet to be overcome, and future possibilities for BC.

p253

proliferation

tissue

abdominal-wall

Bacterial cellulose

microbial cellulose

bone

biomimetic synthesis

Nanocellulose

Biocompatibility

ntana jd

1990

scaffolds

Acetobacter xylinum

Microbial cellulose

biomedical applications

Biomedical

v24-5

biocompatibility

agitated culture

Författare

N. Petersen

University of Virginia

Paul Gatenholm

Chalmers, Kemi- och bioteknik, Polymerteknologi

Applied Microbiology and Biotechnology

0175-7598 (ISSN) 1432-0614 (eISSN)

Vol. 91 1277-1286

Ämneskategorier

Kemi

DOI

10.1007/s00253-011-3432-y