Light-induced cytotoxicity of a photochromic spiropyran
Journal article, 2011
In this work we present a novel water soluble spiropyran photoswitch that can be photonically activated inside live cells from a form that has no significant effect on the cellular survival to a form that induces a dramatic toxic response.
fluorescence
living cells
nanoparticles
photocontrol
proteins
apoptosis
switch
lock-in detection
Author
Jesper Nilsson
Chalmers, Chemical and Biological Engineering, Physical Chemistry
Shiming Li
Chalmers, Chemical and Biological Engineering, Physical Chemistry
B. Onfelt
Karolinska University Hospital
Royal Institute of Technology (KTH)
Joakim Andreasson
Chalmers, Chemical and Biological Engineering, Physical Chemistry
Published in
Chemical Communications
1359-7345 (ISSN) 1364-548X (eISSN)
Vol. 47 Issue 39 p. 11020-11022Research Project(s)
Photochromic Systems for Solid State Molecular Electronic Devices and Light-Activated Cancer Drugs (PHOTOCHROMES)
European Commission (EC) (EC/FP7/203952), 2008-09-01 -- 2013-08-31.
Categorizing
Subject Categories (SSIF 2011)
Chemical Sciences
Identifiers
DOI
10.1039/c1cc13561a