Light-induced cytotoxicity of a photochromic spiropyran
Journal article, 2011

In this work we present a novel water soluble spiropyran photoswitch that can be photonically activated inside live cells from a form that has no significant effect on the cellular survival to a form that induces a dramatic toxic response.

nanoparticles

lock-in detection

switch

living cells

proteins

fluorescence

apoptosis

photocontrol

Author

Jesper Nilsson

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Shiming Li

Chalmers, Chemical and Biological Engineering, Physical Chemistry

B. Onfelt

Royal Institute of Technology (KTH)

Karolinska University Hospital

Joakim Andreasson

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Chemical Communications

1359-7345 (ISSN)

Vol. 47 39 11020-11022

Photochromic Systems for Solid State Molecular Electronic Devices and Light-Activated Cancer Drugs (PHOTOCHROMES)

European Commission (FP7), 2008-09-01 -- 2013-08-31.

Subject Categories

Chemical Sciences

DOI

10.1039/c1cc13561a

More information

Latest update

2/26/2018