Formation of giant unilamellar vesicles from spin-coated lipid films by localized IR heating

Journal article, 2012

We report a novel method for the generation of GUVs (generate unilamellar vesicles) from spin-coated lipid films by means of localized heating. This technique enables GUV formation from both charged and neutral lipid species, as well as from a complex lipid mixture, in various ionic strength conditions. Encapsulation was possible during and after GUV formation.