Owe Orwar

Spatial characterization of a multifunctional pipette for drug delivery in hippocampal brain slices

Probing Structure and Function of Ion Channels Using Limited Proteolysis and Microfluidics

Artificial nanotube connections and transport of molecular cargo between mammalian cells

Probing enzymatic activity inside single cells.

2013

Effect of cholesterol depletion on the pore dilation of TRPV1

Spontaneous shape transformation of free-floating lipid membrane nanotubes

Studying Bending Rigidity of Model Vesicles and Cell Plasma Membrane using Lipid Nanotubes

Kinetics of Diffusion-Mediated DNA Hybridization in Lipid Monolayer Films Determined by Single-Molecule Fluorescence Spectroscopy

A multifunctional pipette for localized drug administration to brain slices

Repair of large area pores in supported double bilayers

2012

Radial Sizing of Lipid Nanotubes Using Membrane Displacement Analysis

2012

Formation of giant unilamellar vesicles from spin-coated lipid films by localized IR heating

Evidence for membrane flow through pores in stacked phospholipid membranes

High-Resolution Micropatterned Teflon AF Substrates for Biocompatible Nanofluidic Devices

Microfluidic Flow Cell for Sequential Digestion of Immobilized Proteoliposomes

NANOFLUIDICS Neither shaken nor stirred

A multifunctional pipette

Molecular phospholipid films on solid supports

Membrane Protrusion Coarsening and Nanotubulation within Giant Unilamellar Vesicles

Nanotube-interconnected liposome networks

Generation of phospholipid vesicle-nanotube networks and transport of molecules therein

2011

Heat-induced formation of single giant unilamellar vesicles

Flow control of thermotropic lipid monolayers

Calcium-ion-controlled nanoparticle-induced tubulation in supported flat phospholipid vesicles

A Microfluidic Pipette for Single-Cell Pharmacology

Single-cell electroporation

A Method for Heat-Stimulated Compression of Poly(N-isopropyl acrylamide) Hydrogels Inside Single Giant Unilamellar Vesicles

Controlling Chemistry in Dynamic Nanoscale Systems

A multi-purpose microfluidic pipette for single-cell analysis

Fractal avalanche ruptures in biological membranes

Protrusive growth and periodic contractile motion in surface-adhered vesicles induced by Ca2+-gradients

Controlling Chemistry by Geometry in Nanoscale Systems

A Microfluidic Diluter Based on Pulse Width Flow Modulation

COMPLEX NANOTUBE-LIPOSOME NETWORKS

Platform for Controlled Supramolecular Nano-Assembly

A giant liposome for single-molecule observation of conformational changes in membrane proteins

Proteomic Analysis of Plasma Membrane Vesicles

Direct Access and Control of the Intracellular Solution Environment in Single Cells

Control of the Release of Freely Diffusing Molecules in Single-Cell Electroporation

Single-Cell Transfection by Electroporation Using an Electrolyte/Plasmid-Filled Capillary

Liposomes: Technologies and Analytical Applications

Transport Phenomena and Chemical Reactions in Nanoscale Surfactant Networks

Thermoactuated diffusion control in soft matter nanofluidic devices

Controlled release of Chol-TEG-DNA from nano- and micropatterned SU-8 surfaces by a spreading lipid film

Controlling the rates of biochemical reactions and signaling networks by shape and volume changes

Shape optimization in lipid nanotube networks

Ligand-specific temperature-dependent shifts in EC50 values for the GABA(A) receptor

Formation and release of circular lipid nanotubes

Injection and Transport of Bacteria in Nanotube-Vesicle Network

Simultaneous maximization of cell permeabilization and viability in single-cell electroporation using an electrolyte-filled capillary

Tunable filtering of chemical signals in a simple nanoscale reaction-diffusion network

Experimentally determining the iR drop in solution at carbon fiber microelectrodes with current interruption and application to single-cell electroporation

Scanning electroporation of selected areas of adherent cell cultures

Direct immobilization of cholesteryl-TEG-modified oligonucleotides onto hydrophobic SU-8 surfaces

Numerical calculations of single-cell electroporation with an electrolyte-filled capillary

Automated control of local solution environments in open-volume microfluidics

Effect of cell size and shape on single-cell electroporation

Controlled formation and mixing of two-dimensional fluids

Dynamic microcompartmentalization of giant unilamellar vesicles by sol gel transition and temperature induced shrinking/swelling of poly(N-isopropyl acrylamide)

Electrophoretic transport of latex particles in lipid nanotubes

Controlling enzymatic reactions by geometry in a biomimetic nanoscale network

Zipper dynamics of surfactant nanotube Upsilon junctions

A biohybrid dynamic random access memory

Controlling the electrochemically active area of carbon fiber microelectrodes by the electrodeposition and selective removal of an insulating photoresist

Controlling desensitized states in ligand-receptor interaction studies with cyclic scanning patch-clamp Protocols

Chemical analysis in nanoscale surfactant networks

Electrophoretic transport in surfactant nanotube networks wired on microfabricated substrates

Direct reconstitution of plasma membrane lipids and proteins in nanotube-vesicle networks

Fluid mixing in growing microscale vesicles conjugated by surfactant nanotubes

Controlled initiation of enzymatic reactions in micrometer-sized biomimetic compartments

A chemical waveform synthesizer

Generation of focused electric field patterns at dielectric surfaces

Microfluidic gradient-generating device for pharmacological profiling

Single-file electrophoretic transport and counting of individual DNA molecules in surfactant nanotubes

Controlled initiation of enzymatic reactions in micrometer-sized biomimetic compartments

Controlling the internal structure of giant unilamellar vesicles by means of reversible temperature dependent sol-gel transition of internalized poly(N-isopropyl acrylamide)

Marangoni transport in lipid nanotubes

Topographic SU 8 Substrates for Immobilization of Three-Dimensional Nanotube-Vesicle Networks

Biomimetic nanoscale reactors and networks

A microfluidics approach to the problem of creating separate solution environments accessible from macroscopic volumes

Micropipet Writing Technique for Production of Two-Dimensional Lipid Bilayer Nanotube-Vesicle Networks on Functionalized and Patterned Surfaces

Nanotube-vesicle networks with functionalized membranes and interiors

Nanofluidic networks based on surfactant membrane technology

Formation of geometrically complex lipid nanotube-vesicle networks of higher-order topologies

Micropipet-assisted formation of microscopic networks of unilamellar lipid bilayer nanotubes and containers

Measurement of the Dynamics of Exocytosis and Vesicle Retrieval at Cell Populations using a Quartz Crystal Microbalance

Increased intra- and extracellular concentrations of gamma-glutamyl-glutamate and related dipeptides in the ischemic rat striatum: involvement of gamma-glutamyl transpeptidase

Extracellular acidic sulfur-containing amino acids and gamma-glutamyl peptides in global ischemia: postischemic recovery of neuronal activity is paralleled by a tetrodotoxin-sensitive increase in cysteine sulfinate in the CA1 of the rat hippocampus

Automated determination of neuroactive acidic sulphur-containing amino acids and gamma-glutamyl peptides using liquid chromatography with fluorescence and electrochemical detection

Changes in extracellular amino acids and spontaneous neuronal activity during ischemia and extended reflow in the CA1 of the rat hippocampus