Site-specific adhesion of Staphylococcus epidermidis (RP12) in Ti-Al-V metal systems
Journal article, 1994

Staphylococcus epidermidis (RP12) adhesion patterns were studied on the following titanium (Ti)-aluminium (Al)-vanadium (V) metal systems: (i) microfabricated samples consisting of Ti, Al and V islands deposited onto Ti or V substrata, (ii) pure Ti, Al and V metals, and (iii) medical grade Ti6Al4-V alloy. All of these surfaces were covered with their respective oxides formed upon exposure of the metals to air. Quantitative analysis of the number of cells bound per unit area indicates that S. epidermidis (RP12) exhibits greatest adhesion to pure V surfaces. When exposed to surfaces having controlled spatial variations in chemical composition on the 10 mu m scale (microfabricated samples), the bacteria preferentially populate V islands versus Ti or Al substrata. In the case of the biphasic Ti6Al4V alloy, the bacteria tend to adhere to V-rich, mixed phase regions and phase boundaries. These findings demonstrate that enhanced and preferential adhesion of S. epidermidis (RP12) occurs on V surfaces in TI-Al-V metal systems and suggest that bacterial interactions are influenced by surface oxide composition.

surfaces

microfabrication

staphylococci

oxides

biomaterials

bacterial adhesion

titanium alloys

Author

B. L. Gabriel

Julie Gold

Chalmers, Applied Physics, Chemical Physics

A. G. Gristina

Bengt Herbert Kasemo

Chalmers, Applied Physics, Chemical Physics

Jukka Lausmaa

Chalmers, Applied Physics, Chemical Physics

C. Harrer

Q. N. Myrvik

Biomaterials

0142-9612 (ISSN)

Vol. 15 8 628-634

Subject Categories

Physical Chemistry

Biomaterials Science

Nano Technology

DOI

10.1016/0142-9612(94)90214-3

More information

Created

10/8/2017