Controlling and Monitoring Orientation of DNA Nanoconstructs on Lipid Surfaces
Journal article, 2013

Its extraordinary self-assembly property, with potential to form nonperiodic structures with unique addressability, makes DNA ideal for fabrication of advanced nanostructures. We here demonstrate the controllable tethering of a hexagonal DNA nanostructure in two distinct orientations at the lipid bilayer of a liposome functioning as a soft-matter support. With polarized light (linear dichroism) applied to the flow-aligned liposomes, we show that the construct is preferentially in a parallel alignment with the lipid surface when two anchors are attached while with one anchor only a perpendicular orientation is observed.

vesicle fusion

nucleic-acids

finite-size

linear dichroism

energy-transfer

wires

nanostructures

reduced dichroism curves

membrane

origami

photonic

Author

Erik Lundberg

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Bobo Feng

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Amir Saeid Mohammadi

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Marcus Wilhelmsson

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Bengt Nordén

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Langmuir

07437463 (ISSN) 15205827 (eISSN)

Vol. 29 1 285-293

Areas of Advance

Nanoscience and Nanotechnology (2010-2017)

Energy

Life Science Engineering (2010-2018)

Materials Science

Subject Categories

Physical Chemistry

Roots

Basic sciences

Infrastructure

Nanofabrication Laboratory

DOI

10.1021/la304178f

More information

Created

10/7/2017