Is the Gly82Ser polymorphism in the RAGE gene relevant to schizophrenia and the personality trait psychoticism?
Journal article, 2012

The receptor for advanced glycation end products (RAGE) is the main receptor for S100B, an astrogial proinflammatory mediator that has been suggested to be involved in the pathophysiology of schizophrenia. To further elucidate the possible relevance of inflammation for mental functions, we investigated a functional polymorphism in the gene coding for RAGE in relation to personality traits and susceptibility to schizophrenia.

Male

Schizophrenia

Single Nucleotide

psychology

S100 Proteins

Polymorphism

genetics

Personality Tests

Middle Aged

Genotype

Female

Immunologic

Case-Control Studies

Humans

genetics

Schizophrenic Psychology

Receptors

Psychotic Disorders

Genetic

genetics

genetics

Personality

genetics

genetics

Polymorphism

DNA

Cohort Studies

Nerve Growth Factors

Author

Petra Suchankova

University of Gothenburg

Jonas Klang

University of Gothenburg

Carin Cavanna

University of Gothenburg

Göran Holm

University of Gothenburg

Staffan Nilsson

Chalmers, Mathematical Sciences, Mathematical Statistics

University of Gothenburg

Erik G Jönsson

Karolinska University Hospital

Agneta Ekman

University of Gothenburg

Journal of Psychiatry and Neuroscience

1180-4882 (ISSN) 1488-2434 (eISSN)

Vol. 37 2 122-128

Subject Categories

Pharmacology and Toxicology

DOI

10.1503/jpn.110024

PubMed

22146151

More information

Created

10/7/2017