Is the Gly82Ser polymorphism in the RAGE gene relevant to schizophrenia and the personality trait psychoticism?
Artikel i vetenskaplig tidskrift, 2012

The receptor for advanced glycation end products (RAGE) is the main receptor for S100B, an astrogial proinflammatory mediator that has been suggested to be involved in the pathophysiology of schizophrenia. To further elucidate the possible relevance of inflammation for mental functions, we investigated a functional polymorphism in the gene coding for RAGE in relation to personality traits and susceptibility to schizophrenia.

Male

Schizophrenia

Single Nucleotide

psychology

S100 Proteins

Polymorphism

genetics

Personality Tests

Middle Aged

Genotype

Female

Immunologic

Case-Control Studies

Humans

genetics

Schizophrenic Psychology

Receptors

Psychotic Disorders

Genetic

genetics

genetics

Personality

genetics

genetics

Polymorphism

DNA

Cohort Studies

Nerve Growth Factors

Författare

Petra Suchankova

Göteborgs universitet

Jonas Klang

Göteborgs universitet

Carin Cavanna

Göteborgs universitet

Göran Holm

Göteborgs universitet

Staffan Nilsson

Chalmers, Matematiska vetenskaper, matematisk statistik

Göteborgs universitet

Erik G Jönsson

Karolinska universitetssjukhuset

Agneta Ekman

Göteborgs universitet

Journal of Psychiatry and Neuroscience

1180-4882 (ISSN) 1488-2434 (eISSN)

Vol. 37 2 122-128

Ämneskategorier

Farmakologi och toxikologi

DOI

10.1503/jpn.110024

PubMed

22146151

Mer information

Skapat

2017-10-07