Carbon-core silver-shell nanodots as sensitizers for phototherapy and radiotherapy
Journal article, 2013

Spherical carbon nanoparticles (carbon nanodots) with a silver shell were investigated as potential sensitizing agents. The cytotoxicity of the combination of ultraviolet radiation or x-rays with the nanodots was examined in cancer cells in vitro. The cell viability decreased following the exposure to the radiation. The carbon nanodots enhanced the radiation effects by significantly reducing the amount of surviving cells compared to that of the cells exposed only to the radiation. Carbon-core silver-shell nanodots can be proposed as a bimodal sensitization platform for biological and medicinal applications employing non-ionizing or ionizing radiation.

Photocatalysis

Radiosensitizer

Radiocatalysis

Photosensitizer

Nanoparticles

Cancer

Author

A. Kleinauskas

Rikshospitalet-Radiumhospitalet HF

Sandra Rocha

Chalmers, Chemical and Biological Engineering, Physical Chemistry

S. Sahu

Clemson University

Y. P. Sun

Clemson University

P. Juzenas

Rikshospitalet-Radiumhospitalet HF

Nanotechnology

0957-4484 (ISSN) 1361-6528 (eISSN)

Vol. 24 32

Areas of Advance

Nanoscience and Nanotechnology (2010-2017)

Subject Categories

Physical Chemistry

Nano Technology

DOI

10.1088/0957-4484/24/32/325103

More information

Created

10/7/2017