Thermal migration of molecular lipid films as a contactless fabrication strategy for lipid nanotube networks
Journal article, 2013

We demonstrate the contactless generation of lipid nanotube networks by means of thermally induced migration of flat giant unilamellar vesicles (FGUVs), covering micro-scale areas on oxidized aluminum surfaces. A temperature gradient with a reach of 20 mm was generated using a focused IR laser, leading to a surface adhesion gradient, along which FGUVs could be relocated. We report on suitable lipid-substrate combinations, highlighting the critical importance of the electrostatic interactions between the engineered substrate and the membrane for reversible migration of intact vesicles.

Author

Irep Gözen

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Mehrnaz Shaali

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Alar Ainla

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Bahanur Örtmen

Chalmers, Chemical and Biological Engineering

I. Poldsalu

University of Tartu

K. Kustanovich

Gavin Jeffries

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Zoran Konkoli

Chalmers, Applied Physics, Electronics Material and Systems Laboratory

P. Dommersnes

Centre for Advanced Study (CAS)

Aldo Jesorka

Chalmers, Chemical and Biological Engineering, Physical Chemistry

Lab on a Chip - Miniaturisation for Chemistry and Biology

1473-0197 (ISSN) 1473-0189 (eISSN)

Vol. 13 19 3822-3826

Subject Categories

Biochemistry and Molecular Biology

DOI

10.1039/c3lc50391g

More information

Latest update

1/18/2019