Thermal migration of molecular lipid films as a contactless fabrication strategy for lipid nanotube networks
Journal article, 2013
We demonstrate the contactless generation of lipid nanotube networks by means of thermally induced migration of flat giant unilamellar vesicles (FGUVs), covering micro-scale areas on oxidized aluminum surfaces. A temperature gradient with a reach of 20 mm was generated using a focused IR laser, leading to a surface adhesion gradient, along which FGUVs could be relocated. We report on suitable lipid-substrate combinations, highlighting the critical importance of the electrostatic interactions between the engineered substrate and the membrane for reversible migration of intact vesicles.
Author
Irep Gözen
Chalmers, Chemical and Biological Engineering, Physical Chemistry
Mehrnaz Shaali
Chalmers, Chemical and Biological Engineering, Physical Chemistry
Alar Ainla
Chalmers, Chemical and Biological Engineering, Physical Chemistry
Bahanur Örtmen
Chalmers, Chemical and Biological Engineering
I. Poldsalu
University of Tartu
K. Kustanovich
Gavin Jeffries
Chalmers, Chemical and Biological Engineering, Physical Chemistry
Zoran Konkoli
Chalmers, Applied Physics, Electronics Material and Systems
P. Dommersnes
Centre for Advanced Study (CAS)
Aldo Jesorka
Chalmers, Chemical and Biological Engineering, Physical Chemistry
Lab on a Chip - Miniaturisation for Chemistry and Biology
1473-0197 (ISSN) 1473-0189 (eISSN)
Vol. 13 19 3822-3826Subject Categories
Biochemistry and Molecular Biology
DOI
10.1039/c3lc50391g